HitPredict

Interactor 1: PABP4 (Q13310)
Polyadenylate-binding protein 4 (PABP-4) (Poly(A)-binding protein 4) (Activated-platelet protein 1) (APP-1) (Inducible poly(A)-binding protein) (iPABP)
Gene: PABPC4

Interactor 2: CSN5 (Q92905)
COP9 signalosome complex subunit 5 (SGN5) (Signalosome subunit 5) (EC 3.4.-.-) (Jun activation domain-binding protein 1)
Gene: COPS5

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.62	0.60	0.611

Property	Details
Experiments	31950832, 21145461
Identification Methods	affinity chromatography technology, tandem affinity purification
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005737 - cytoplasm GO:0005829 - cytosol GO:0006412 - translation
Homologous interactions	6

Homologous interactions

Color coding for hit scores

	1 644 Hs			1 334
+	Hs
		516624 PABP1_HUMAN (1-644): 0: 542: 74.54		CSN5_HUMAN (1-334): 6.64e-131: 378: 100.00
+	Hs
		582416 NUCL_HUMAN (2-89): 1.4e-20: 98.4: 31.82		CSN5_HUMAN (1-334): 6.64e-131: 378: 100.00
+	Sc
		376827 PABP_YEAST (2-290): 4.28e-66: 228: 30.07		RPN11_YEAST (39-333): 9.57e-75: 234: 29.14
+	Hs
		680473 TIA1_HUMAN (4-109): 7.62e-12: 69.5: 24.53		CSN5_HUMAN (1-334): 6.64e-131: 378: 100.00
+	Hs
		130734 NUCL_HUMAN (2-89): 1.4e-20: 98.4: 31.82		PSDE_HUMAN (50-331): 1.67e-79: 246: 31.51
+	Hs
		176940 NUCL_HUMAN (2-89): 1.4e-20: 98.4: 31.82		EIF3H_HUMAN (52-320): 2.17e-66: 214: 18.57