HitPredict

Interactor 1: PABP4 (Q13310)
Polyadenylate-binding protein 4 (PABP-4) (Poly(A)-binding protein 4) (Activated-platelet protein 1) (APP-1) (Inducible poly(A)-binding protein) (iPABP)
Gene: PABPC4

Interactor 2: MKRN2 (Q9H000)
E3 ubiquitin-protein ligase makorin-2 (EC 2.3.2.27) (RING finger protein 62) (RING-type E3 ubiquitin transferase makorin-2)
Gene: MKRN2

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.56	1.00	0.754

Property	Details
Experiments	29395067, 32460013
Identification Methods	proximity labelling technology, affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	RRM_1~zf-CCCH
Common GO terms	GO:0003723 - RNA binding GO:0005634 - nucleus GO:0005737 - cytoplasm
Homologous interactions	11

Homologous interactions

Color coding for hit scores

	1 644 Hs			1 416
+	Hs
		516684 PABP1_HUMAN (1-644): 0: 542: 74.54		MKRN2_HUMAN (1-416): 5.68e-170: 484: 100.00
+	Hs
		1031488 PABP4_HUMAN (1-644): 0: 585: 100.00		MKRN1_HUMAN (3-398): 4.09e-149: 433: 45.71
+	Hs
		516728 PABP1_HUMAN (1-644): 0: 542: 74.54		MKRN1_HUMAN (3-398): 4.09e-149: 433: 45.71
+	Hs
		1023456 PABP4_HUMAN (1-644): 0: 585: 100.00		MKRN3_HUMAN (3-351): 8.84e-109: 331: 39.77
+	Hs
		516487 PABP1_HUMAN (1-644): 0: 542: 74.54		MKRN3_HUMAN (3-351): 8.84e-109: 331: 39.77
+	Hs
		1023561 PABP3_HUMAN (1-644): 7.04e-175: 513: 68.98		MKRN3_HUMAN (3-351): 8.84e-109: 331: 39.77
+	Hs
		1031384 PABP4_HUMAN (1-644): 0: 585: 100.00		ZC3H3_HUMAN (4-140): 1.11e-10: 65.6: 25.18
+	Hs
		1221460 PABP3_HUMAN (1-644): 7.04e-175: 513: 68.98		ZC3H3_HUMAN (4-140): 1.11e-10: 65.6: 25.18
+	Hs
		1288624 PABP5_HUMAN (4-93): 1.22e-15: 81: 23.33		MKRN2_HUMAN (1-416): 5.68e-170: 484: 100.00
+	Dm
		597087 PABP_DROME (2-464): 6.23e-64: 224: 22.09		Q9VP20_DROME (28-386): 1.95e-106: 321: 33.70
+	Hs
		1288644 PABP5_HUMAN (4-93): 1.22e-15: 81: 23.33		MKRN1_HUMAN (3-398): 4.09e-149: 433: 45.71