HitPredict

Interactor 1: PABP4 (Q13310)
Polyadenylate-binding protein 4 (PABP-4) (Poly(A)-binding protein 4) (Activated-platelet protein 1) (APP-1) (Inducible poly(A)-binding protein) (iPABP)
Gene: PABPC4

Interactor 2: PUF60 (Q9UHX1)
Poly(U)-binding-splicing factor PUF60 (60 kDa poly(U)-binding-splicing factor) (FUSE-binding protein-interacting repressor) (FBP-interacting repressor) (Ro-binding protein 1) (RoBP1) (Siah-binding protein 1) (Siah-BP1)
Gene: PUF60

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.44	1.00	0.665

Property	Details
Experiments	17353931
Identification Methods	affinity chromatography technology, anti bait coimmunoprecipitation
Interaction Type	physical association

Property	Details
Interacting Pfam domains	RRM_1~RRM_1
Common GO terms	GO:0003723 - RNA binding
Homologous interactions	18

Homologous interactions

Color coding for hit scores

	1 644 Hs			1 559
+	Hs
		516730 PABP1_HUMAN (1-644): 0: 542: 74.54		PUF60_HUMAN (1-559): 2.1e-103: 324: 100.00
+	Hs
		1031328 PABP4_HUMAN (1-644): 0: 585: 100.00		RBM39_HUMAN (113-555): 5.61e-70: 235: 19.78
+	Hs
		516518 PABP1_HUMAN (1-644): 0: 542: 74.54		RBM39_HUMAN (113-555): 5.61e-70: 235: 19.78
+	Hs
		1020249 PABP4_HUMAN (1-644): 0: 585: 100.00		ELAV2_HUMAN (223-553): 1.56e-45: 165: 14.80
+	Hs
		516484 PABP1_HUMAN (1-644): 0: 542: 74.54		ELAV2_HUMAN (223-553): 1.56e-45: 165: 14.80
+	Hs
		516635 PABP1_HUMAN (1-644): 0: 542: 74.54		PABP5_HUMAN (133-308): 3.43e-45: 165: 23.86
+	Hs
		1031413 PABP4_HUMAN (1-644): 0: 585: 100.00		CELF1_HUMAN (98-214): 1.29e-17: 87.5: 26.50
+	Hs
		474021 PABP4_HUMAN (1-644): 0: 585: 100.00		PAB4L_HUMAN (479-559): 3.69e-14: 76.1: 20.99
+	Hs
		1119141 PAP1L_HUMAN (1-636): 6.79e-165: 487: 63.89		PABP5_HUMAN (133-308): 3.43e-45: 165: 23.86
+	Hs
		516495 PABP4_HUMAN (1-644): 0: 585: 100.00		PABP1_HUMAN (457-550): 3.84e-10: 64.5: 10.64
+	Hs
		516621 PABP1_HUMAN (1-644): 0: 542: 74.54		CELF1_HUMAN (98-214): 1.29e-17: 87.5: 26.50
+	Hs
		516689 PABP1_HUMAN (1-644): 0: 542: 74.54		PABP3_HUMAN (479-559): 6.17e-13: 73.4: 19.75
+	Hs
		516339 PABP1_HUMAN (1-644): 0: 542: 74.54		PABP1_HUMAN (457-550): 3.84e-10: 64.5: 10.64
+	Hs
		1054312 ELAV3_HUMAN (3-272): 2.13e-40: 153: 19.15		RBM39_HUMAN (113-555): 5.61e-70: 235: 19.78
+	Hs
		1020259 ELAV3_HUMAN (3-272): 2.13e-40: 153: 19.15		ELAV2_HUMAN (223-553): 1.56e-45: 165: 14.80
+	Hs
		1055876 ELAV3_HUMAN (3-272): 2.13e-40: 153: 19.15		PABP5_HUMAN (133-308): 3.43e-45: 165: 23.86
+	Hs
		474019 PAB4L_HUMAN (192-380): 4.58e-38: 146: 31.05		ELAV2_HUMAN (223-553): 1.56e-45: 165: 14.80
+	Sc
		376562 PABP_YEAST (2-290): 4.28e-66: 228: 30.07		PABP_YEAST (465-553): 7.06e-12: 69.9: 16.85