HitPredict

Interactor 1: ATM (Q13315)
Serine-protein kinase ATM (EC 2.7.11.1) (Ataxia telangiectasia mutated) (A-T mutated)
Gene: ATM

Interactor 2: C5AR2 (Q9P296)
C5a anaphylatoxin chemotactic receptor 2 (Complement component 5a receptor 2) (G-protein coupled receptor 77)
Gene: C5AR2

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.47	0.50	0.489

Property	Details
Experiments	28514442
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	-
Homologous interactions	17

Homologous interactions

Color coding for hit scores

	1 3056 Hs			1 337
+	Hs
		598935 ATM_HUMAN (1-3056): 0: 3806: 100.00		FPR1_HUMAN (34-326): 2.06e-75: 237: 27.85
+	Hs
		895616 ATM_HUMAN (1-3056): 0: 3806: 100.00		CXCR4_HUMAN (2-298): 9.99e-72: 228: 22.58
+	Hs
		723296 ATM_HUMAN (1-3056): 0: 3806: 100.00		APJ_HUMAN (26-336): 6.02e-67: 216: 23.21
+	Hs
		600759 ATM_HUMAN (1-3056): 0: 3806: 100.00		C5AR1_HUMAN (3-336): 2.69e-63: 206: 34.48
+	Hs
		723037 ATM_HUMAN (1-3056): 0: 3806: 100.00		OPRM_HUMAN (11-333): 1.48e-61: 203: 18.29
+	Hs
		798422 ATM_HUMAN (1-3056): 0: 3806: 100.00		LPAR6_HUMAN (41-314): 2.45e-15: 77.8: 21.50
+	Hs
		723038 ATR_HUMAN (1223-3056): 0: 1214: 20.34		OPRM_HUMAN (11-333): 1.48e-61: 203: 18.29
+	Hs
		598924 MTOR_HUMAN (1846-3055): 0: 843: 16.65		FPR1_HUMAN (34-326): 2.06e-75: 237: 27.85
+	Hs
		787434 MTOR_HUMAN (1846-3055): 0: 843: 16.65		CXCR4_HUMAN (2-298): 9.99e-72: 228: 22.58
+	Hs
		787552 MTOR_HUMAN (1846-3055): 0: 843: 16.65		CML1_HUMAN (2-334): 1.35e-68: 220: 27.22
+	Hs
		723279 MTOR_HUMAN (1846-3055): 0: 843: 16.65		APJ_HUMAN (26-336): 6.02e-67: 216: 23.21
+	Hs
		598934 PRKDC_HUMAN (2005-3056): 6.86e-155: 545: 17.20		FPR1_HUMAN (34-326): 2.06e-75: 237: 27.85
+	Hs
		429015 PRKDC_HUMAN (2005-3056): 6.86e-155: 545: 17.20		ADRB2_HUMAN (2-330): 1.21e-65: 214: 15.63
+	Hs
		666304 PRKDC_HUMAN (2005-3056): 6.86e-155: 545: 17.20		NK3R_HUMAN (1-335): 3.01e-63: 209: 16.90
+	Hs
		787363 PK3CB_HUMAN (2385-3011): 9.82e-99: 348: 13.76		CXCR4_HUMAN (2-298): 9.99e-72: 228: 22.58
+	Hs
		822537 PK3CG_HUMAN (2437-2965): 4.25e-88: 316: 16.14		CXCR4_HUMAN (2-298): 9.99e-72: 228: 22.58
+	Mm
		936867 PK3CG_MOUSE (2446-2965): 4.69e-87: 313: 16.04		CXCR4_MOUSE (2-298): 6.63e-71: 226: 24.60