HitPredict

Interactor 1: GRB10 (Q13322)
Growth factor receptor-bound protein 10 (GRB10 adapter protein) (Insulin receptor-binding protein Grb-IR)
Gene: GRB10

Interactor 2: ABI1 (Q8IZP0)
Abl interactor 1 (Abelson interactor 1) (Abi-1) (Abl-binding protein 4) (AblBP4) (Eps8 SH3 domain-binding protein) (Eps8-binding protein) (Nap1-binding protein) (Nap1BP) (Spectrin SH3 domain-binding protein 1) (e3B1)
Gene: ABI1

Species: Homo sapiens

Source: mint

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.41	1.00	0.647

Property	Details
Experiments	20598684
Identification Methods	array technology
Interaction Type	direct interaction

Property	Details
Interacting Pfam domains	PH~SH3_1, SH2~SH3_1
Common GO terms	GO:0005829 - cytosol
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 594 Hs			1 508
+	Hs
		548732 VAV_HUMAN (36-594): 3.93e-139: 426: 14.11		ABI1_HUMAN (1-508): 3.82e-124: 374: 100.00
+	Hs
		1173959 RAPH1_HUMAN (34-484): 6.16e-107: 350: 23.94		ABI1_HUMAN (1-508): 3.82e-124: 374: 100.00
+	Hs
		855808 VAV2_HUMAN (40-588): 1.7e-95: 313: 12.26		ABI1_HUMAN (1-508): 3.82e-124: 374: 100.00
+	Hs
		1173971 RAPH1_HUMAN (34-484): 6.16e-107: 350: 23.94		ABI2_HUMAN (1-508): 1.41e-81: 264: 59.84
+	Hs
		996567 ITK_HUMAN (293-589): 1.9e-60: 213: 15.47		ABI1_HUMAN (1-508): 3.82e-124: 374: 100.00
+	Ce
		711888 MIG10_CAEEL (30-526): 1.08e-108: 345: 22.31		Q10929_CAEEL (3-503): 2.93e-67: 225: 28.94
+	Hs
		411788 LCK_HUMAN (420-589): 7.66e-49: 179: 19.66		ABI1_HUMAN (1-508): 3.82e-124: 374: 100.00
+	Hs
		412258 FYN_HUMAN (441-591): 5.64e-47: 174: 20.38		ABI1_HUMAN (1-508): 3.82e-124: 374: 100.00
+	Hs
		433413 YES_HUMAN (441-592): 9.17e-47: 174: 20.89		ABI1_HUMAN (1-508): 3.82e-124: 374: 100.00
+	Hs
		523060 SRC_HUMAN (443-590): 9.55e-47: 174: 22.08		ABI1_HUMAN (1-508): 3.82e-124: 374: 100.00
+	Hs
		203198 LCK_HUMAN (420-589): 7.66e-49: 179: 19.66		SYNJ1_HUMAN (38-463): 1.36e-41: 161: 11.55
+	Hs
		789012 TEC_HUMAN (293-590): 2.81e-52: 191: 12.33		ASAP1_HUMAN (107-505): 8.23e-33: 135: 16.83
+	Hs
		433350 YES_HUMAN (441-592): 9.17e-47: 174: 20.89		SRC8_HUMAN (291-502): 1.23e-34: 138: 20.72
+	Hs
		522981 SRC_HUMAN (443-590): 9.55e-47: 174: 22.08		SRC8_HUMAN (291-502): 1.23e-34: 138: 20.72
+	Hs
		412404 FYN_HUMAN (441-591): 5.64e-47: 174: 20.38		ASAP1_HUMAN (107-505): 8.23e-33: 135: 16.83
+	Hs
		523197 SRC_HUMAN (443-590): 9.55e-47: 174: 22.08		ASAP1_HUMAN (107-505): 8.23e-33: 135: 16.83
+	Hs
		433354 YES_HUMAN (441-592): 9.17e-47: 174: 20.89		LASP1_HUMAN (285-503): 9.91e-33: 127: 19.28
+	Mm
		411921 LCK_MOUSE (420-589): 1.66e-48: 178: 20.23		HCLS1_MOUSE (266-503): 2.48e-29: 122: 20.07
+	Mm
		763381 FYN_MOUSE (441-591): 5.64e-47: 174: 20.38		HCLS1_MOUSE (266-503): 2.48e-29: 122: 20.07
+	Hs
		166024 FYN_HUMAN (441-591): 5.64e-47: 174: 20.38		SYNJ2_HUMAN (39-458): 2.1e-26: 115: 13.88