HitPredict

Interactor 1: MTA1 (Q13330)
Metastasis-associated protein MTA1
Gene: MTA1

Interactor 2: HDAC2 (Q92769)
Histone deacetylase 2 (HD2) (EC 3.5.1.98) (Protein deacylase HDAC2) (EC 3.5.1.-)
Gene: HDAC2

Species: Homo sapiens

Source: mint

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.97 1.00 0.986

The method score is based on:

Property Details
Experiments 12920132, 11146623, 24981860, 37071682, 12431981, 17671180, 20651739, 21670149, 12493763, 30737378, 35271311, 38270169, 9885572, 21258344, 23752268, 26949739, 26028330, 18451879
Identification Methods affinity chromatography technology, cross-linking study, pull down, anti tag coimmunoprecipitation, anti bait coimmunoprecipitation
Interaction Type physical association, direct interaction, association

The annotation score is based on:

Property Details
Interacting Pfam domains ELM2~Hist_deacetyl, Hist_deacetyl~Myb_DNA-binding
Common GO terms GO:0000122 - negative regulation of transcription by RNA polymerase II
GO:0003682 - chromatin binding
GO:0005634 - nucleus
GO:0005654 - nucleoplasm
GO:0005737 - cytoplasm
and 9 others

more...
Homologous interactions 20

Homologous interactions (Top 20)

Color coding for hit scores

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Hs

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Service provided by Combinatics, Japan

Last updated: 15 Jul 2024