HitPredict

Interactor 1: MTA1 (Q13330)
Metastasis-associated protein MTA1
Gene: MTA1

Interactor 2: TRPS1 (Q9UHF7)
Zinc finger transcription factor Trps1 (Tricho-rhino-phalangeal syndrome type I protein) (Zinc finger protein GC79)
Gene: TRPS1

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.47	1.00	0.691

Property	Details
Experiments	33961781
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	GATA~GATA
Common GO terms	GO:0000122 - negative regulation of transcription by RNA polymerase II GO:0005634 - nucleus GO:0005654 - nucleoplasm
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 715 Hs			1 1281
+	Hs
		296168 MTA2_HUMAN (1-715): 0: 741: 57.55		TRPS1_HUMAN (1-1281): 0: 1888: 100.00
+	Hs
		1312040 MTA3_HUMAN (1-592): 0: 716: 68.98		TRPS1_HUMAN (1-1281): 0: 1888: 100.00
+	Hs
		1355449 RCOR1_HUMAN (165-532): 5.9e-67: 230: 18.60		TRPS1_HUMAN (1-1281): 0: 1888: 100.00
+	Hs
		1031846 MTA1_HUMAN (1-715): 0: 939: 100.00		IKZF1_HUMAN (781-1272): 5.18e-107: 349: 19.45
+	Hs
		1031971 MTA1_HUMAN (1-715): 0: 939: 100.00		IKZF3_HUMAN (850-1268): 4.38e-82: 280: 18.63
+	Hs
		798887 MTA1_HUMAN (1-715): 0: 939: 100.00		GATA4_HUMAN (870-1060): 3.74e-45: 171: 28.36
+	Hs
		296013 MTA2_HUMAN (1-715): 0: 741: 57.55		IKZF1_HUMAN (781-1272): 5.18e-107: 349: 19.45
+	Hs
		1033722 MTA3_HUMAN (1-592): 0: 716: 68.98		IKZF1_HUMAN (781-1272): 5.18e-107: 349: 19.45
+	Hs
		296171 MTA2_HUMAN (1-715): 0: 741: 57.55		IKZF3_HUMAN (850-1268): 4.38e-82: 280: 18.63
+	Hs
		295956 MTA2_HUMAN (1-715): 0: 741: 57.55		GATA4_HUMAN (870-1060): 3.74e-45: 171: 28.36
+	Mm
		570301 MTA2_MOUSE (1-715): 0: 747: 57.28		GATA1_MOUSE (804-1033): 5.18e-40: 155: 20.21
+	Hs
		798992 MTA3_HUMAN (1-592): 0: 716: 68.98		GATA4_HUMAN (870-1060): 3.74e-45: 171: 28.36
+	Hs
		620565 MTA3_HUMAN (1-592): 0: 716: 68.98		GATA3_HUMAN (870-1017): 3.94e-36: 144: 27.03
+	Hs
		1350409 RCOR3_HUMAN (167-532): 3.91e-75: 252: 17.71		IKZF3_HUMAN (850-1268): 4.38e-82: 280: 18.63
+	Hs
		554529 RCOR3_HUMAN (167-532): 3.91e-75: 252: 17.71		GATA1_HUMAN (804-1046): 1.3e-37: 148: 17.55
+	Hs
		620586 RCOR3_HUMAN (167-532): 3.91e-75: 252: 17.71		GATA3_HUMAN (870-1017): 3.94e-36: 144: 27.03
+	Hs
		620592 RCOR1_HUMAN (165-532): 5.9e-67: 230: 18.60		GATA3_HUMAN (870-1017): 3.94e-36: 144: 27.03
+	Hs
		620436 RCOR3_HUMAN (167-532): 3.91e-75: 252: 17.71		GATA2_HUMAN (821-1072): 2.62e-27: 119: 20.60
+	Hs
		620439 RCOR1_HUMAN (165-532): 5.9e-67: 230: 18.60		GATA2_HUMAN (821-1072): 2.62e-27: 119: 20.60
+	Hs
		620368 MDEAS_HUMAN (157-483): 5.94e-46: 178: 14.17		GATA2_HUMAN (821-1072): 2.62e-27: 119: 20.60