HitPredict

Interactor 1: EIF3I (Q13347)
Eukaryotic translation initiation factor 3 subunit I (eIF3i) (Eukaryotic translation initiation factor 3 subunit 2) (TGF-beta receptor-interacting protein 1) (TRIP-1) (eIF-3-beta) (eIF3 p36)
Gene: EIF3I

Interactor 2: DCA10 (Q5QP82)
DDB1- and CUL4-associated factor 10 (WD repeat-containing protein 32)
Gene: DCAF10

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.74	0.80	0.770

Property	Details
Experiments	28514442, 26186194, 33961781
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	ANAPC4_WD40~WD40
Common GO terms	-
Homologous interactions	17

Homologous interactions

Color coding for hit scores

	1 325 Hs			1 559
+	Sp
		999842 TUP12_SCHPO (4-220): 2.53e-65: 217: 20.89		TUP11_SCHPO (193-558): 4.12e-60: 211: 12.33
+	Hs
		903197 EIF3I_HUMAN (1-325): 3.67e-93: 281: 100.00		WDR5_HUMAN (404-558): 4.98e-21: 96.3: 13.55
+	Hs
		1240442 POC1A_HUMAN (81-324): 1.17e-56: 190: 14.63		POC1B_HUMAN (286-554): 4.01e-40: 154: 9.03
+	Sp
		999838 TUP11_SCHPO (171-324): 1.02e-32: 129: 17.39		TUP11_SCHPO (193-558): 4.12e-60: 211: 12.33
+	Hs
		903349 WDR5_HUMAN (180-325): 1.26e-38: 141: 15.65		WDR5B_HUMAN (12-325): 5.26e-48: 171: 12.50
+	Hs
		903502 WDR5_HUMAN (180-325): 1.26e-38: 141: 15.65		SKI8_HUMAN (130-325): 4.55e-40: 149: 26.40
+	Hs
		197071 PRP4_HUMAN (95-325): 1.03e-46: 166: 11.67		SNR40_HUMAN (333-557): 6.41e-23: 102: 9.21
+	Hs
		196984 PRP4_HUMAN (95-325): 1.03e-46: 166: 11.67		WDR5_HUMAN (404-558): 4.98e-21: 96.3: 13.55
+	Hs
		903428 WDR5_HUMAN (180-325): 1.26e-38: 141: 15.65		SNR40_HUMAN (333-557): 6.41e-23: 102: 9.21
+	Hs
		903077 WDR5_HUMAN (180-325): 1.26e-38: 141: 15.65		WDR5_HUMAN (404-558): 4.98e-21: 96.3: 13.55
+	Dm
		1358845 WDS_DROME (177-325): 5.55e-38: 140: 16.67		WDS_DROME (396-557): 1.55e-19: 92.5: 12.96
+	Hs
		903551 WDR5_HUMAN (180-325): 1.26e-38: 141: 15.65		NLE1_HUMAN (390-556): 5.65e-18: 89: 13.30
+	Sc
		630844 NLE1_YEAST (2-125): 1.27e-34: 133: 21.43		NLE1_YEAST (336-558): 4.3e-19: 92.5: 9.82
+	Hs
		792949 WDR5_HUMAN (180-325): 1.26e-38: 141: 15.65		LIS1_HUMAN (400-555): 6.63e-16: 81.7: 12.82
+	Hs
		209416 WDR5_HUMAN (180-325): 1.26e-38: 141: 15.65		PLRG1_HUMAN (390-555): 2.21e-14: 77.8: 9.28
+	Sc
		744629 EIF3I_YEAST (141-325): 9.4e-30: 117: 13.36		TAF5_YEAST (381-555): 1.12e-15: 82.5: 12.78
+	Hs
		209467 SNR40_HUMAN (3-122): 1.87e-26: 108: 20.93		PLRG1_HUMAN (390-555): 2.21e-14: 77.8: 9.28