HitPredict

Interactor 1: EIF3I (Q13347)
Eukaryotic translation initiation factor 3 subunit I (eIF3i) (Eukaryotic translation initiation factor 3 subunit 2) (TGF-beta receptor-interacting protein 1) (TRIP-1) (eIF-3-beta) (eIF3 p36)
Gene: EIF3I

Interactor 2: PKHA7 (Q6IQ23)
Pleckstrin homology domain-containing family A member 7 (PH domain-containing family A member 7)
Gene: PLEKHA7

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.33	1.00	0.575

Property	Details
Experiments	28877994
Identification Methods	anti bait coimmunoprecipitation
Interaction Type	association

Property	Details
Interacting Pfam domains	PH~WD40
Common GO terms	GO:0005829 - cytosol GO:0070062 - extracellular exosome
Homologous interactions	16

Homologous interactions

Color coding for hit scores

	1 325 Hs			1 1121
+	Hs
		903302 WDR5_HUMAN (180-325): 1.26e-38: 141: 15.65		PKHA7_HUMAN (1-1121): 2.81e-180: 560: 100.00
+	Hs
		1153322 FBXW7_HUMAN (5-75): 4.23e-09: 59.6: 24.05		PKHA7_HUMAN (1-1121): 2.81e-180: 560: 100.00
+	Hs
		1153471 STRAP_HUMAN (186-316): 4.07e-09: 58.9: 20.15		PKHA7_HUMAN (1-1121): 2.81e-180: 560: 100.00
+	Hs
		1240465 POC1A_HUMAN (81-324): 1.17e-56: 190: 14.63		PKHA5_HUMAN (11-1074): 3.5e-95: 330: 29.45
+	Hs
		125431 EIF3I_HUMAN (1-325): 3.67e-93: 281: 100.00		WWP2_HUMAN (8-203): 2.64e-43: 173: 24.39
+	Hs
		1032155 EIF3I_HUMAN (1-325): 3.67e-93: 281: 100.00		PKHA4_HUMAN (113-465): 8.31e-38: 154: 28.84
+	Hs
		876342 WDR5_HUMAN (180-325): 1.26e-38: 141: 15.65		AFAD_HUMAN (329-1063): 1.33e-45: 182: 11.19
+	Hs
		197087 PRP4_HUMAN (95-325): 1.03e-46: 166: 11.67		PKHA4_HUMAN (113-465): 8.31e-38: 154: 28.84
+	Hs
		125310 WDR5_HUMAN (180-325): 1.26e-38: 141: 15.65		WWP2_HUMAN (8-203): 2.64e-43: 173: 24.39
+	Hs
		903516 WDR5_HUMAN (180-325): 1.26e-38: 141: 15.65		PKHA4_HUMAN (113-465): 8.31e-38: 154: 28.84
+	Hs
		1288303 SNR40_HUMAN (3-122): 1.87e-26: 108: 20.93		PKHA4_HUMAN (113-465): 8.31e-38: 154: 28.84
+	Hs
		793030 LIS1_HUMAN (1-82): 2.95e-21: 95.1: 25.61		PKHA4_HUMAN (113-465): 8.31e-38: 154: 28.84
+	Hs
		125811 STRAP_HUMAN (186-316): 4.07e-09: 58.9: 20.15		WWP2_HUMAN (8-203): 2.64e-43: 173: 24.39
+	Hs
		1331701 STRAP_HUMAN (186-316): 4.07e-09: 58.9: 20.15		PKHA4_HUMAN (113-465): 8.31e-38: 154: 28.84
+	Hs
		1056932 SNR40_HUMAN (3-122): 1.87e-26: 108: 20.93		MDC1_HUMAN (281-1110): 6.34e-20: 98.8: 10.84
+	Sc
		765276 EIF3I_YEAST (141-325): 9.4e-30: 117: 13.36		RSP5_YEAST (29-320): 3.05e-17: 89.3: 13.99