HitPredict

Interactor 1: EIF3I (Q13347)
Eukaryotic translation initiation factor 3 subunit I (eIF3i) (Eukaryotic translation initiation factor 3 subunit 2) (TGF-beta receptor-interacting protein 1) (TRIP-1) (eIF-3-beta) (eIF3 p36)
Gene: EIF3I

Interactor 2: PSPC1 (Q8WXF1)
Paraspeckle component 1 (Paraspeckle protein 1)
Gene: PSPC1

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.47	0.60	0.536

Property	Details
Experiments	35271311
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0003723 - RNA binding
Homologous interactions	10

Homologous interactions

Color coding for hit scores

	1 325 Hs			1 523
+	Hs
		903390 WDR5_HUMAN (180-325): 1.26e-38: 141: 15.65		PSPC1_HUMAN (1-523): 7.74e-85: 273: 100.00
+	Hs
		516438 WDR5_HUMAN (180-325): 1.26e-38: 141: 15.65		PABP1_HUMAN (4-522): 4.65e-70: 237: 14.16
+	Hs
		903241 WDR5_HUMAN (180-325): 1.26e-38: 141: 15.65		NONO_HUMAN (50-523): 4.22e-68: 228: 57.60
+	Hs
		613398 WDR5_HUMAN (180-325): 1.26e-38: 141: 15.65		SFPQ_HUMAN (53-523): 3.05e-59: 210: 54.14
+	Hs
		1263497 FBXW7_HUMAN (5-75): 4.23e-09: 59.6: 24.05		PSPC1_HUMAN (1-523): 7.74e-85: 273: 100.00
+	Sc
		376807 EIF3I_YEAST (141-325): 9.4e-30: 117: 13.36		PABP_YEAST (4-373): 1.42e-48: 178: 14.85
+	Hs
		1069762 FBXW7_HUMAN (5-75): 4.23e-09: 59.6: 24.05		NONO_HUMAN (50-523): 4.22e-68: 228: 57.60
+	Hs
		613543 FBXW7_HUMAN (5-75): 4.23e-09: 59.6: 24.05		SFPQ_HUMAN (53-523): 3.05e-59: 210: 54.14
+	Hs
		903196 WDR5_HUMAN (180-325): 1.26e-38: 141: 15.65		PABP4_HUMAN (3-149): 2.52e-27: 118: 18.83
+	Hs
		1222300 SNR40_HUMAN (3-122): 1.87e-26: 108: 20.93		RAVR1_HUMAN (84-234): 5.69e-14: 76.4: 23.35