HitPredict

Interactor 1: EIF3I (Q13347)
Eukaryotic translation initiation factor 3 subunit I (eIF3i) (Eukaryotic translation initiation factor 3 subunit 2) (TGF-beta receptor-interacting protein 1) (TRIP-1) (eIF-3-beta) (eIF3 p36)
Gene: EIF3I

Interactor 2: FZR1 (Q9UM11)
Fizzy-related protein homolog (Fzr) (CDC20-like protein 1) (Cdh1/Hct1 homolog) (hCDH1)
Gene: FZR1

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	1.00	0.618

Property	Details
Experiments	33306668
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	ANAPC4_WD40~ANAPC4_WD40, ANAPC4_WD40~WD40
Common GO terms	GO:0005829 - cytosol
Homologous interactions	18

Homologous interactions

Color coding for hit scores

	1 325 Hs			1 496
+	Dm
		1358859 WDS_DROME (177-325): 5.55e-38: 140: 16.67		FBXW7_DROME (20-496): 6.04e-89: 298: 17.46
+	Hs
		903197 EIF3I_HUMAN (1-325): 3.67e-93: 281: 100.00		WDR5_HUMAN (389-496): 1.49e-26: 111: 18.35
+	Mm
		1351642 EIF3I_MOUSE (1-325): 1.41e-92: 279: 99.39		FZR1_MOUSE (319-495): 2.95e-25: 110: 18.68
+	Hs
		903418 WDR5_HUMAN (180-325): 1.26e-38: 141: 15.65		FBXW7_HUMAN (87-424): 1.7e-71: 242: 18.68
+	Hs
		903551 WDR5_HUMAN (180-325): 1.26e-38: 141: 15.65		NLE1_HUMAN (52-385): 3.28e-60: 207: 16.32
+	Hs
		197071 PRP4_HUMAN (95-325): 1.03e-46: 166: 11.67		SNR40_HUMAN (32-339): 1.33e-49: 175: 15.89
+	Hs
		792949 WDR5_HUMAN (180-325): 1.26e-38: 141: 15.65		LIS1_HUMAN (309-495): 7.12e-53: 185: 19.68
+	Hs
		903428 WDR5_HUMAN (180-325): 1.26e-38: 141: 15.65		SNR40_HUMAN (32-339): 1.33e-49: 175: 15.89
+	Hs
		1240442 POC1A_HUMAN (81-324): 1.17e-56: 190: 14.63		POC1B_HUMAN (31-259): 4.34e-30: 124: 13.19
+	Hs
		196984 PRP4_HUMAN (95-325): 1.03e-46: 166: 11.67		WDR5_HUMAN (389-496): 1.49e-26: 111: 18.35
+	Hs
		197107 PRP4_HUMAN (95-325): 1.03e-46: 166: 11.67		FZR1_HUMAN (319-495): 6.65e-25: 109: 18.68
+	Sp
		999842 TUP11_SCHPO (171-324): 1.02e-32: 129: 17.39		TUP12_SCHPO (346-495): 7.82e-30: 125: 20.89
+	Hs
		903077 WDR5_HUMAN (180-325): 1.26e-38: 141: 15.65		WDR5_HUMAN (389-496): 1.49e-26: 111: 18.35
+	Hs
		903603 WDR5_HUMAN (180-325): 1.26e-38: 141: 15.65		FZR1_HUMAN (319-495): 6.65e-25: 109: 18.68
+	Dm
		1358845 WDS_DROME (177-325): 5.55e-38: 140: 16.67		WDS_DROME (389-496): 1.28e-24: 106: 17.43
+	Hs
		1288386 SNR40_HUMAN (3-122): 1.87e-26: 108: 20.93		FZR1_HUMAN (319-495): 6.65e-25: 109: 18.68
+	Hs
		903349 WDR5_HUMAN (180-325): 1.26e-38: 141: 15.65		WDR5B_HUMAN (408-495): 1.82e-11: 67.3: 16.15
+	Hs
		903176 WDR5_HUMAN (180-325): 1.26e-38: 141: 15.65		CDC20_HUMAN (395-494): 7.34e-10: 63: 16.67