Interactor 1: PPIL2 (Q13356)
RING-type E3 ubiquitin-protein ligase PPIL2 (EC 2.3.2.27) (CYC4) (Cyclophilin-60) (Cyclophilin-like protein Cyp-60) (Cyp60) (hCyP-60) (Probable inactive peptidyl-prolyl cis-trans isomerase-like 2) (PPIase) (Rotamase PPIL2)
Gene: PPIL2

Interactor 2: PPIE (Q9UNP9)
Peptidyl-prolyl cis-trans isomerase E (PPIase E) (EC 5.2.1.8) (Cyclophilin E) (Cyclophilin-33) (Rotamase E)
Gene: PPIE

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score Annotation score Interaction score
0.38 1.00 0.618

The method score is based on:

Property Details
Experiments 27684187
Identification Methods affinity chromatography technology
Interaction Type physical association

The annotation score is based on:

Property Details
Interacting Pfam domains Pro_isomerase~Pro_isomerase, Pro_isomerase~RRM_1
Common GO terms GO:0005634 - nucleus
GO:0005654 - nucleoplasm
GO:0005737 - cytoplasm
GO:0005886 - plasma membrane
GO:0006457 - protein folding
and 1 others

more...

Homologous interactions 7

Homologous interactions

Color coding for hit scores

1 520
Hs

1 301
+ Hs
+ Ce
+ Hs
+ Zm
+ Zm
+ Sc
+ Hs

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Last updated: 15 Jul 2024