HitPredict

Interactor 1: CTBP1 (Q13363)
C-terminal-binding protein 1 (CtBP1) (EC 1.1.1.-)
Gene: CTBP1

Interactor 2: CTBP1 (Q13363)
C-terminal-binding protein 1 (CtBP1) (EC 1.1.1.-)
Gene: CTBP1

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.94 1.00 0.974

The method score is based on:

Property Details
Experiments 25416956, 27107012, 21102443, 35016035, 19754958, 20361981, 21988832, 24722188, 31515488, 31041561
Identification Methods two hybrid, affinity chromatography technology, two hybrid array, barcode fusion genetics two hybrid, validated two hybrid, anti tag coimmunoprecipitation
Interaction Type direct interaction, physical association, association

The annotation score is based on:

Property Details
Interacting Pfam domains 2-Hacid_dh~2-Hacid_dh, 2-Hacid_dh~2-Hacid_dh_C, 2-Hacid_dh_C~2-Hacid_dh_C
Common GO terms GO:0000122 - negative regulation of transcription by RNA polymerase II
GO:0001221 - transcription coregulator binding
GO:0001222 - transcription corepressor binding
GO:0003682 - chromatin binding
GO:0003713 - transcription coactivator activity
and 21 others

more...
Homologous interactions 15

Homologous interactions

Color coding for hit scores

1 440
Hs

1 440
+ Hs
+ Hs
+ Hs
+ Mm
+ Hs
+ Dm
+ At
+ Sc
+ Sc
+ Sc
+ Cj
+ Ec
+ At
+ Ec
+ Hp

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Last updated: 15 Jul 2024