HitPredict

Interactor 1: CTBP1 (Q13363)
C-terminal-binding protein 1 (CtBP1) (EC 1.1.1.-)
Gene: CTBP1

Interactor 2: RCOR2 (Q8IZ40)
REST corepressor 2
Gene: RCOR2

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.74	0.60	0.667

Property	Details
Experiments	26186194, 28514442, 33961781
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0003714 - transcription corepressor activity GO:0006357 - regulation of transcription by RNA polymerase II GO:0045892 - negative regulation of DNA-templated transcription
Homologous interactions	9

Homologous interactions

Color coding for hit scores

	1 440 Hs			1 523
+	Hs
		881228 CTBP2_HUMAN (10-439): 0: 538: 80.23		RCOR2_HUMAN (1-523): 2.13e-143: 424: 100.00
+	Hs
		1032660 CTBP1_HUMAN (1-440): 0: 547: 100.00		RCOR3_HUMAN (46-520): 8.7e-129: 386: 57.20
+	Hs
		296012 CTBP1_HUMAN (1-440): 0: 547: 100.00		MTA2_HUMAN (12-512): 1.27e-102: 324: 17.50
+	Hs
		1032672 CTBP1_HUMAN (1-440): 0: 547: 100.00		RCOR1_HUMAN (16-425): 1.79e-102: 318: 51.44
+	Hs
		295972 CTBP2_HUMAN (10-439): 0: 538: 80.23		MTA2_HUMAN (12-512): 1.27e-102: 324: 17.50
+	Hs
		881330 CTBP2_HUMAN (10-439): 0: 538: 80.23		RCOR1_HUMAN (16-425): 1.79e-102: 318: 51.44
+	Hs
		881161 CTBP2_HUMAN (10-439): 0: 538: 80.23		MTA1_HUMAN (26-474): 1.9e-97: 311: 17.00
+	Hs
		91457 CTBP1_HUMAN (1-440): 0: 547: 100.00		E7EQY4_HUMAN (17-359): 3.52e-91: 290: 18.55
+	Hs
		1032718 CTBP1_HUMAN (1-440): 0: 547: 100.00		NCOR2_HUMAN (133-521): 1.5e-11: 69.3: 10.24