HitPredict

Interactor 1: CTBP1 (Q13363)
C-terminal-binding protein 1 (CtBP1) (EC 1.1.1.-)
Gene: CTBP1

Interactor 2: FOXP1 (Q9H334)
Forkhead box protein P1 (Mac-1-regulated forkhead) (MFH)
Gene: FOXP1

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.54	0.60	0.571

Property	Details
Experiments	14701752, 31041561
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0006357 - regulation of transcription by RNA polymerase II GO:0045892 - negative regulation of DNA-templated transcription
Homologous interactions	8

Homologous interactions

Color coding for hit scores

	1 440 Hs			1 677
+	Hs
		881286 CTBP2_HUMAN (10-439): 0: 538: 80.23		FOXP1_HUMAN (1-677): 0: 670: 100.00
+	Hs
		178965 CTBP1_HUMAN (1-440): 0: 547: 100.00		FOXP2_HUMAN (1-677): 0: 563: 60.19
+	Hs
		178957 CTBP2_HUMAN (10-439): 0: 538: 80.23		FOXP2_HUMAN (1-677): 0: 563: 60.19
+	Hs
		964176 CTBP1_HUMAN (1-440): 0: 547: 100.00		FOXK2_HUMAN (364-657): 1.47e-50: 188: 19.81
+	Hs
		952804 CTBP1_HUMAN (1-440): 0: 547: 100.00		FOXK1_HUMAN (367-650): 2.19e-44: 171: 22.77
+	Hs
		881208 CTBP2_HUMAN (10-439): 0: 538: 80.23		FOXI2_HUMAN (369-656): 2.64e-50: 179: 19.54
+	Hs
		206836 CTBP1_HUMAN (1-440): 0: 547: 100.00		FOXO3_HUMAN (468-642): 3.42e-42: 164: 32.46
+	Hs
		126451 CTBP2_HUMAN (10-439): 0: 538: 80.23		FOXE1_HUMAN (416-658): 8.61e-45: 166: 23.20