HitPredict

Interactor 1: CTBP1 (Q13363)
C-terminal-binding protein 1 (CtBP1) (EC 1.1.1.-)
Gene: CTBP1

Interactor 2: IKZF2 (Q9UKS7)
Zinc finger protein Helios (Ikaros family zinc finger protein 2)
Gene: IKZF2

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.48	0.60	0.541

Property	Details
Experiments	24722188
Identification Methods	two hybrid, two hybrid array
Interaction Type	direct interaction, physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0006357 - regulation of transcription by RNA polymerase II
Homologous interactions	9

Homologous interactions

Color coding for hit scores

	1 440 Hs			1 526
+	Hs
		881332 CTBP2_HUMAN (10-439): 0: 538: 80.23		IKZF2_HUMAN (1-526): 0: 696: 100.00
+	Hs
		1032605 CTBP1_HUMAN (1-440): 0: 547: 100.00		IKZF4_HUMAN (9-524): 3.72e-165: 482: 54.22
+	Hs
		1032385 CTBP1_HUMAN (1-440): 0: 547: 100.00		IKZF1_HUMAN (31-526): 2.39e-164: 478: 54.20
+	Hs
		881163 CTBP2_HUMAN (10-439): 0: 538: 80.23		IKZF1_HUMAN (31-526): 2.39e-164: 478: 54.20
+	Hs
		881333 CTBP2_HUMAN (10-439): 0: 538: 80.23		IKZF3_HUMAN (10-524): 5.02e-160: 466: 46.52
+	Rn
		88975 CTBP1_RAT (14-440): 0: 526: 98.36		D4A9W4_RAT (38-526): 1.28e-159: 466: 54.47
+	Mm
		292178 CTBP1_MOUSE (1-440): 0: 545: 98.64		Q8C5P6_MOUSE (31-227): 4.19e-78: 248: 66.50
+	Mm
		881367 CTBP2_MOUSE (10-439): 0: 535: 80.00		Q8C5P6_MOUSE (31-227): 4.19e-78: 248: 66.50
+	Hs
		881179 CTBP2_HUMAN (10-439): 0: 538: 80.23		ZNF79_HUMAN (166-517): 3.13e-25: 110: 15.91