HitPredict

Interactor 1: CTBP1 (Q13363)
C-terminal-binding protein 1 (CtBP1) (EC 1.1.1.-)
Gene: CTBP1

Interactor 2: DYR1B (Q9Y463)
Dual specificity tyrosine-phosphorylation-regulated kinase 1B (EC 2.7.12.1) (Minibrain-related kinase) (Mirk protein kinase)
Gene: DYRK1B

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.47	0.60	0.536

Property	Details
Experiments	32707033
Identification Methods	affinity chromatography technology, pull down
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0003713 - transcription coactivator activity GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0006468 - protein phosphorylation
Homologous interactions	11

Homologous interactions

Color coding for hit scores

	1 440 Hs			1 629
+	Hs
		881350 CTBP2_HUMAN (10-439): 0: 538: 80.23		DYR1B_HUMAN (1-629): 2.33e-171: 503: 100.00
+	Hs
		1032395 CTBP1_HUMAN (1-440): 0: 547: 100.00		DYR1A_HUMAN (19-594): 3.53e-135: 415: 63.57
+	Hs
		647854 CTBP2_HUMAN (10-439): 0: 538: 80.23		MARK3_HUMAN (57-629): 1.59e-123: 384: 18.49
+	Hs
		681826 CTBP1_HUMAN (1-440): 0: 547: 100.00		AKT1_HUMAN (6-429): 7.87e-119: 363: 18.41
+	Hs
		197300 SERA_HUMAN (29-404): 9.81e-121: 363: 29.23		DYR1A_HUMAN (19-594): 3.53e-135: 415: 63.57
+	Hs
		1032606 CTBP1_HUMAN (1-440): 0: 547: 100.00		HIPK2_HUMAN (111-434): 3.93e-52: 196: 36.31
+	Mm
		292437 CTBP2_MOUSE (10-439): 0: 535: 80.00		HIPK1_MOUSE (111-430): 1.53e-54: 202: 37.31
+	Hs
		881285 CTBP2_HUMAN (10-439): 0: 538: 80.23		HIPK2_HUMAN (111-434): 3.93e-52: 196: 36.31
+	Mm
		881370 CTBP2_MOUSE (10-439): 0: 535: 80.00		HIPK2_MOUSE (111-434): 9.48e-52: 194: 36.01
+	Hs
		197229 SERA_HUMAN (29-404): 9.81e-121: 363: 29.23		CDK2_HUMAN (108-376): 5.32e-119: 357: 27.82
+	At
		188691 CTBP_ARATH (18-345): 2.27e-96: 304: 29.67		KSG7_ARATH (111-475): 9.76e-115: 349: 27.11