Interactor 1: PDE3B (Q13370)
cGMP-inhibited 3',5'-cyclic phosphodiesterase 3B (EC 3.1.4.17) (CGIPDE1) (CGIP1) (Cyclic GMP-inhibited phosphodiesterase B) (CGI-PDE B)
Gene: PDE3B
Interactor 2: PDE3A (Q14432)
cGMP-inhibited 3',5'-cyclic phosphodiesterase 3A (EC 3.1.4.17) (Cyclic GMP-inhibited phosphodiesterase A) (CGI-PDE A) (cGMP-inhibited cAMP phosphodiesterase) (cGI-PDE)
Gene: PDE3A
Species: Homo sapiens
Source: intact
Category: High-throughput
Confidence: High
| Method score | Annotation score | Interaction score |
|---|---|---|
| 0.47 | 1.00 | 0.691 |
The method score is based on:
| Property | Details |
|---|---|
| Experiments | 33961781 |
| Identification Methods | affinity chromatography technology, anti tag coimmunoprecipitation |
| Interaction Type | physical association, association |
The annotation score is based on:
| Property | Details |
|---|---|
| Interacting Pfam domains | PDEase_I~PDEase_I |
| Common GO terms | GO:0004114 - 3',5'-cyclic-nucleotide phosphodiesterase activity GO:0004115 - 3',5'-cyclic-AMP phosphodiesterase activity GO:0004119 - cGMP-inhibited cyclic-nucleotide phosphodiesterase activity GO:0005829 - cytosol GO:0007186 - G protein-coupled receptor signaling pathway and 6 others more... |
| Homologous interactions | 8 |
Homologous interactions
Color coding for hit scores 
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Last updated: 15 Jul 2024
