HitPredict

Interactor 1: PDE3B (Q13370)
cGMP-inhibited 3',5'-cyclic phosphodiesterase 3B (EC 3.1.4.17) (CGIPDE1) (CGIP1) (Cyclic GMP-inhibited phosphodiesterase B) (CGI-PDE B)
Gene: PDE3B

Interactor 2: LRRT1 (Q86UE6)
Leucine-rich repeat transmembrane neuronal protein 1
Gene: LRRTM1

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.65	0.60	0.628

Property	Details
Experiments	28514442, 33961781
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005783 - endoplasmic reticulum
Homologous interactions	4

Homologous interactions

Color coding for hit scores

	1 1112 Hs			1 522
+	Hs
		200343 PDE3B_HUMAN (1-1112): 0: 1539: 100.00		LRRT2_HUMAN (2-247): 1.47e-35: 141: 21.95
+	Hs
		1032804 PDE3B_HUMAN (1-1112): 0: 1539: 100.00		LGR4_HUMAN (49-223): 4.79e-21: 99.3: 24.58
+	Hs
		1053713 PDE3A_HUMAN (122-1105): 0: 1058: 44.22		LRIG3_HUMAN (34-328): 2.25e-53: 196: 24.77
+	Hs
		995933 PDE4D_HUMAN (381-1100): 0: 551: 21.92		RXFP1_HUMAN (115-314): 1.13e-13: 75.9: 29.13