HitPredict

Interactor 1: PHLP (Q13371)
Phosducin-like protein (PHLP)
Gene: PDCL

Interactor 2: GBG12 (Q9UBI6)
Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-12
Gene: GNG12

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.47	0.60	0.536

Property	Details
Experiments	33961781
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0007165 - signal transduction
Homologous interactions	9

Homologous interactions

Color coding for hit scores

	1 301 Hs			1 72
+	Hs
		929151 PHLP_HUMAN (1-301): 1.36e-118: 344: 100.00		GBG3_HUMAN (3-72): 1.94e-26: 93.2: 57.75
+	Hs
		887105 PHLP_HUMAN (1-301): 1.36e-118: 344: 100.00		GBG2_HUMAN (5-72): 3.25e-26: 92.8: 62.32
+	Hs
		837676 PHLP_HUMAN (1-301): 1.36e-118: 344: 100.00		GBG4_HUMAN (6-72): 2e-24: 88.2: 57.35
+	Hs
		837690 PHLP_HUMAN (1-301): 1.36e-118: 344: 100.00		GBG10_HUMAN (6-72): 4.05e-24: 87.4: 44.78
+	Hs
		929162 PHLP_HUMAN (1-301): 1.36e-118: 344: 100.00		GBG5_HUMAN (6-72): 9.85e-23: 83.6: 46.27
+	Hs
		117 PHLP_HUMAN (1-301): 1.36e-118: 344: 100.00		A0A024R161_HUMAN (21-72): 1.57e-18: 75.5: 40.39
+	Hs
		929137 PHLP_HUMAN (1-301): 1.36e-118: 344: 100.00		GBG1_HUMAN (13-71): 8.37e-19: 73.9: 41.67
+	Hs
		902494 PHLP_HUMAN (1-301): 1.36e-118: 344: 100.00		GBG11_HUMAN (13-71): 1.16e-18: 73.5: 44.07
+	Hs
		280478 GLRX3_HUMAN (171-250): 2.53e-20: 91: 23.46		GBG13_HUMAN (11-72): 6.26e-21: 79.3: 27.42