HitPredict

Interactor 1: JIP2 (Q13387)
C-Jun-amino-terminal kinase-interacting protein 2 (JIP-2) (JNK-interacting protein 2) (Islet-brain-2) (IB-2) (JNK MAP kinase scaffold protein 2) (Mitogen-activated protein kinase 8-interacting protein 2)
Gene: MAPK8IP2

Interactor 2: JIP2 (Q13387)
C-Jun-amino-terminal kinase-interacting protein 2 (JIP-2) (JNK-interacting protein 2) (Islet-brain-2) (IB-2) (JNK MAP kinase scaffold protein 2) (Mitogen-activated protein kinase 8-interacting protein 2)
Gene: MAPK8IP2

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.38 1.00 0.618

The method score is based on:

Property Details
Experiments 10490659
Identification Methods affinity chromatography technology
Interaction Type physical association

The annotation score is based on:

Property Details
Interacting Pfam domains PID~PID, SH3_9~SH3_9
Common GO terms GO:0000165 - MAPK cascade
GO:0001540 - amyloid-beta binding
GO:0001662 - behavioral fear response
GO:0005078 - MAP-kinase scaffold activity
GO:0005198 - structural molecule activity
and 23 others

more...
Homologous interactions 14

Homologous interactions

Color coding for hit scores

1 824
Hs

1 824
+ Hs
+ Hs
+ Rn
+ Dm
+ Hs
+ Hs
+ Hs
+ Ce
+ Rn
+ Hs
+ Mm
+ Dm
+ Hs
+ Hs

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024