HitPredict

Interactor 1: JIP2 (Q13387)
C-Jun-amino-terminal kinase-interacting protein 2 (JIP-2) (JNK-interacting protein 2) (Islet-brain-2) (IB-2) (JNK MAP kinase scaffold protein 2) (Mitogen-activated protein kinase 8-interacting protein 2)
Gene: MAPK8IP2

Interactor 2: KS6B2 (Q9UBS0)
Ribosomal protein S6 kinase beta-2 (S6K-beta-2) (S6K2) (EC 2.7.11.1) (70 kDa ribosomal protein S6 kinase 2) (P70S6K2) (p70-S6K 2) (S6 kinase-related kinase) (SRK) (Serine/threonine-protein kinase 14B) (p70 ribosomal S6 kinase beta) (S6K-beta) (p70 S6 kinase beta) (p70 S6K-beta) (p70 S6KB) (p70-beta)
Gene: RPS6KB2

Species: Homo sapiens

Source: mint

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.43	0.60	0.508

Property	Details
Experiments	21900206
Identification Methods	two hybrid
Interaction Type	direct interaction, physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005737 - cytoplasm
Homologous interactions	7

Homologous interactions

Color coding for hit scores

	1 824 Hs			1 482
+	Hs
		568650 JIP2_HUMAN (1-824): 9.09e-151: 464: 100.00		KAPCA_HUMAN (31-387): 1.3e-144: 419: 34.17
+	Hs
		1186099 MICA3_HUMAN (23-631): 7.8e-36: 149: 12.64		AKT3_HUMAN (6-391): 7.6e-154: 447: 39.85
+	Hs
		682191 SH3R1_HUMAN (59-663): 1.98e-29: 128: 12.93		AKT2_HUMAN (26-391): 9.02e-155: 450: 41.24
+	Hs
		681922 SH3R1_HUMAN (59-663): 1.98e-29: 128: 12.93		AKT1_HUMAN (5-391): 6.01e-153: 445: 39.19
+	Rn
		812709 JIP1_RAT (13-351): 3.28e-18: 91.4: 19.14		AKT1_RAT (5-391): 3.1e-153: 446: 39.19
+	Hs
		682078 JIP1_HUMAN (13-351): 1.71e-16: 86: 18.75		AKT1_HUMAN (5-391): 6.01e-153: 445: 39.19
+	Hs
		969116 OGFR_HUMAN (98-491): 5.93e-10: 65: 18.14		KPCE_HUMAN (2-395): 2.02e-145: 435: 34.23