HitPredict

Interactor 1: UB2V1 (Q13404)
Ubiquitin-conjugating enzyme E2 variant 1 (UEV-1) (CROC-1) (TRAF6-regulated IKK activator 1 beta Uev1A)
Gene: UBE2V1

Interactor 2: PELI1 (Q96FA3)
E3 ubiquitin-protein ligase pellino homolog 1 (Pellino-1) (EC 2.3.2.27) (Pellino-related intracellular-signaling molecule) (RING-type E3 ubiquitin transferase pellino homolog 1)
Gene: PELI1

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.71	0.60	0.655

Property	Details
Experiments	36179399, 21204785, 19734906
Identification Methods	pull down
Interaction Type	direct interaction

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005829 - cytosol GO:0043123 - positive regulation of canonical NF-kappaB signal transduction GO:0070534 - protein K63-linked ubiquitination
Homologous interactions	5

Homologous interactions

Color coding for hit scores

	1 147 Hs			1 418
+	Hs
		849407 UB2D1_HUMAN (12-147): 1.15e-57: 177: 24.27		PELI1_HUMAN (1-418): 0: 817: 100.00
+	Hs
		919823 UB2D2_HUMAN (12-146): 1.25e-56: 175: 22.96		PELI1_HUMAN (1-418): 0: 817: 100.00
+	Hs
		895877 UB2D3_HUMAN (12-146): 3.82e-56: 173: 22.96		PELI1_HUMAN (1-418): 0: 817: 100.00
+	Hs
		930350 UBC9_HUMAN (9-145): 2.94e-54: 169: 21.01		PELI1_HUMAN (1-418): 0: 817: 100.00
+	Hs
		1033119 UB2V1_HUMAN (1-147): 1.08e-54: 170: 100.00		PELI3_HUMAN (3-418): 0: 696: 66.67