HitPredict

Interactor 1: UB2V1 (Q13404)
Ubiquitin-conjugating enzyme E2 variant 1 (UEV-1) (CROC-1) (TRAF6-regulated IKK activator 1 beta Uev1A)
Gene: UBE2V1

Interactor 2: OTUB1 (Q96FW1)
Ubiquitin thioesterase OTUB1 (EC 3.4.19.12) (Deubiquitinating enzyme OTUB1) (OTU domain-containing ubiquitin aldehyde-binding protein 1) (Otubain-1) (hOTU1) (Ubiquitin-specific-processing protease OTUB1)
Gene: OTUB1

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.41	1.00	0.646

Property	Details
Experiments	22367539
Identification Methods	pull down
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	Peptidase_C65~UQ_con
Common GO terms	GO:0005654 - nucleoplasm GO:0005829 - cytosol GO:0070062 - extracellular exosome
Homologous interactions	9

Homologous interactions

Color coding for hit scores

	1 147 Hs			1 271
+	Hs
		1079009 UB2V2_HUMAN (4-147): 8.54e-72: 213: 88.89		OTUB1_HUMAN (1-271): 3.25e-150: 422: 100.00
+	Hs
		1291615 UB2D4_HUMAN (12-146): 4.26e-58: 178: 24.44		OTUB1_HUMAN (1-271): 3.25e-150: 422: 100.00
+	Hs
		849408 UB2D1_HUMAN (12-147): 1.15e-57: 177: 24.27		OTUB1_HUMAN (1-271): 3.25e-150: 422: 100.00
+	Hs
		919824 UB2D2_HUMAN (12-146): 1.25e-56: 175: 22.96		OTUB1_HUMAN (1-271): 3.25e-150: 422: 100.00
+	Hs
		895878 UB2D3_HUMAN (12-146): 3.82e-56: 173: 22.96		OTUB1_HUMAN (1-271): 3.25e-150: 422: 100.00
+	Hs
		1282326 UB2E3_HUMAN (1-145): 1.38e-54: 172: 22.76		OTUB1_HUMAN (1-271): 3.25e-150: 422: 100.00
+	Hs
		1291545 UB2E2_HUMAN (2-145): 1.8e-54: 171: 23.61		OTUB1_HUMAN (1-271): 3.25e-150: 422: 100.00
+	Ce
		715115 UBC2_CAEEL (12-146): 2.35e-57: 176: 24.44		OTUBL_CAEEL (3-271): 2.76e-122: 352: 34.42
+	Hs
		851868 UB2E1_HUMAN (7-124): 1.45e-12: 63.8: 29.37		OTUB1_HUMAN (1-271): 3.25e-150: 422: 100.00