HitPredict

Interactor 1: G3X9U2 (G3X9U2)
Zinc finger protein 446
Gene: Zfp446

Interactor 2: ISL2 (Q9CXV0)
Insulin gene enhancer protein ISL-2 (Islet-2)
Gene: ISL2

Species: Mus musculus

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.481

Property	Details
Experiments	20211142
Identification Methods	two hybrid
Interaction Type	direct interaction

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0000981 - DNA-binding transcription factor activity, RNA polymerase II-specific GO:0005634 - nucleus GO:0046872 - metal ion binding
Homologous interactions	18

Homologous interactions

Color coding for hit scores

	1 423 Mm			1 359
+	Mm
		1208069 Q8C9M8_MOUSE (1-423): 8.74e-124: 370: 100.00		ISL2_MOUSE (1-359): 1.69e-85: 264: 100.00
+	Mm
		1208071 Q8C9M8_MOUSE (1-423): 8.74e-124: 370: 100.00		LHX9_MOUSE (10-325): 4.1e-59: 197: 27.22
+	Mm
		103327 G3X9U2_MOUSE (1-423): 1.89e-123: 366: 100.00		LHX9_MOUSE (10-325): 4.1e-59: 197: 27.22
+	Hs
		855972 ZN135_HUMAN (41-423): 3.52e-101: 316: 15.06		LMO4_HUMAN (15-165): 1.89e-54: 177: 38.13
+	Mm
		292005 Q8C9M8_MOUSE (1-423): 8.74e-124: 370: 100.00		LMX1B_MOUSE (7-83): 7.55e-18: 85.8: 19.48
+	Mm
		103322 G3X9U2_MOUSE (1-423): 1.89e-123: 366: 100.00		LMX1B_MOUSE (7-83): 7.55e-18: 85.8: 19.48
+	Hs
		822658 ZKSC4_HUMAN (109-422): 7.65e-66: 221: 16.98		LHX1_HUMAN (26-356): 5.2e-58: 195: 26.54
+	Hs
		304690 ZN202_HUMAN (221-422): 3.11e-50: 181: 18.56		LMO4_HUMAN (15-165): 1.89e-54: 177: 38.13
+	Hs
		638487 ZNF84_HUMAN (103-423): 3.68e-48: 176: 19.12		RBTN1_HUMAN (17-144): 5.24e-53: 174: 38.17
+	Hs
		822701 ZSC21_HUMAN (315-423): 1.74e-37: 143: 28.45		LHX1_HUMAN (26-356): 5.2e-58: 195: 26.54
+	Hs
		563560 ZNF24_HUMAN (345-423): 4.56e-29: 118: 29.11		RBTN1_HUMAN (17-144): 5.24e-53: 174: 38.17
+	Hs
		154549 ZN213_HUMAN (365-423): 1.64e-24: 107: 35.59		LMO4_HUMAN (15-165): 1.89e-54: 177: 38.13
+	Hs
		846679 ZNF84_HUMAN (103-423): 3.68e-48: 176: 19.12		LMO3_HUMAN (27-148): 1.79e-26: 104: 40.16
+	Hs
		903756 ZN397_HUMAN (359-422): 1.61e-21: 98.5: 37.50		LMO4_HUMAN (15-165): 1.89e-54: 177: 38.13
+	Hs
		182424 ZSC9_HUMAN (173-423): 6.32e-37: 140: 19.39		LMO3_HUMAN (27-148): 1.79e-26: 104: 40.16
+	Mm
		1129997 ZSC26_MOUSE (94-285): 6.38e-13: 72: 11.74		Q8VD35_MOUSE (155-354): 1.21e-42: 151: 18.64
+	Hs
		1357658 ZSC21_HUMAN (315-423): 1.74e-37: 143: 28.45		LHX6_HUMAN (7-84): 1.63e-12: 69.6: 19.23
+	Hs
		1078405 ZKSC8_HUMAN (55-230): 9.28e-22: 99.6: 11.23		LMO3_HUMAN (27-148): 1.79e-26: 104: 40.16