Interactor 1: DC1I2 (Q13409)
Cytoplasmic dynein 1 intermediate chain 2 (Cytoplasmic dynein intermediate chain 2) (Dynein intermediate chain 2, cytosolic) (DH IC-2)
Gene: DYNC1I2

Interactor 2: DYHC1 (Q14204)
Cytoplasmic dynein 1 heavy chain 1 (Cytoplasmic dynein heavy chain 1) (Dynein heavy chain, cytosolic)
Gene: DYNC1H1

Species: Homo sapiens

Source: mint

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.94 1.00 0.973

The method score is based on:

Property Details
Experiments 26496610, 35271311, 35235311, 28514442, 28718761, 34079125, 33961781, 37071682, 24986880
Identification Methods affinity chromatography technology, cross-linking study, proximity labelling technology, anti tag coimmunoprecipitation, electron microscopy, molecular sieving
Interaction Type physical association, association

The annotation score is based on:

Property Details
Interacting Pfam domains AAA_8~WD40, AAA_9~WD40, DHC_N1~WD40
Common GO terms GO:0005813 - centrosome
GO:0005829 - cytosol
GO:0005868 - cytoplasmic dynein complex
GO:0005874 - microtubule
GO:0030286 - dynein complex
Homologous interactions 14

Homologous interactions

Color coding for hit scores

1 638
Hs

1 4646
+ Mm
+ Hs
+ Mm
+ Hs
+ Hs
+ Dm
+ Dm
+ Hs
+ Ce
+ Ce
+ Cr
+ Cr
+ Cr
+ Cr

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024