HitPredict

Interactor 1: DC1I2 (Q13409)
Cytoplasmic dynein 1 intermediate chain 2 (Cytoplasmic dynein intermediate chain 2) (Dynein intermediate chain 2, cytosolic) (DH IC-2)
Gene: DYNC1I2

Interactor 2: WDR76 (Q9H967)
WD repeat-containing protein 76
Gene: WDR76

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.80	0.553

Property	Details
Experiments	27248496
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	WD40~WD40
Common GO terms	-
Homologous interactions	18

Homologous interactions

Color coding for hit scores

	1 638 Hs			1 626
+	Hs
		792979 DC1I2_HUMAN (1-638): 3.3e-143: 432: 100.00		LIS1_HUMAN (118-478): 6.33e-51: 183: 9.73
+	Hs
		148046 DC1I1_HUMAN (1-638): 2.67e-129: 396: 75.04		LIS1_HUMAN (118-478): 6.33e-51: 183: 9.73
+	Sc
		630844 NLE1_YEAST (150-632): 8.04e-72: 242: 12.26		NLE1_YEAST (358-624): 3.12e-61: 213: 10.10
+	Sp
		999838 TUP11_SCHPO (365-624): 8.77e-49: 182: 14.29		TUP11_SCHPO (47-623): 8.38e-83: 273: 11.53
+	Ce
		219875 O45087_CAEEL (7-629): 1.21e-99: 319: 34.53		LIN53_CAEEL (251-477): 2.75e-20: 95.7: 15.73
+	Hs
		903349 WDR5B_HUMAN (367-626): 3.82e-61: 208: 16.15		WDR5_HUMAN (435-622): 2.2e-42: 157: 12.23
+	Hs
		1346954 NLE1_HUMAN (466-625): 5.77e-36: 143: 14.55		NLE1_HUMAN (181-575): 1.3e-63: 219: 12.70
+	Hs
		245633 TBL1R_HUMAN (317-624): 4.89e-57: 202: 13.11		TBL1X_HUMAN (248-479): 3.7e-39: 153: 13.67
+	Sp
		999842 TUP11_SCHPO (365-624): 8.77e-49: 182: 14.29		TUP12_SCHPO (120-480): 2.27e-44: 169: 11.52
+	Hs
		245546 TBL1X_HUMAN (364-623): 2.38e-45: 171: 15.30		TBL1X_HUMAN (248-479): 3.7e-39: 153: 13.67
+	Hs
		792949 WDR5_HUMAN (112-459): 1.1e-36: 141: 10.11		LIS1_HUMAN (118-478): 6.33e-51: 183: 9.73
+	Hs
		245630 TBL1Y_HUMAN (364-623): 5.21e-45: 169: 14.55		TBL1X_HUMAN (248-479): 3.7e-39: 153: 13.67
+	Hs
		903551 NLE1_HUMAN (466-625): 5.77e-36: 143: 14.55		WDR5_HUMAN (435-622): 2.2e-42: 157: 12.23
+	Hs
		903077 WDR5_HUMAN (112-459): 1.1e-36: 141: 10.11		WDR5_HUMAN (435-622): 2.2e-42: 157: 12.23
+	Hs
		196984 WDR5_HUMAN (112-459): 1.1e-36: 141: 10.11		PRP4_HUMAN (401-624): 5.45e-40: 155: 15.09
+	Dm
		1358845 WDS_DROME (368-626): 4.13e-62: 211: 16.60		WDS_DROME (132-392): 6.5e-14: 75.5: 11.57
+	Ce
		954090 LIS1_CAEEL (418-624): 5.99e-40: 153: 13.68		LIN53_CAEEL (251-477): 2.75e-20: 95.7: 15.73
+	Hs
		903171 WDR5_HUMAN (112-459): 1.1e-36: 141: 10.11		RBBP4_HUMAN (233-477): 2.84e-19: 92.6: 14.55