HitPredict

Interactor 1: DC1I2 (Q13409)
Cytoplasmic dynein 1 intermediate chain 2 (Cytoplasmic dynein intermediate chain 2) (Dynein intermediate chain 2, cytosolic) (DH IC-2)
Gene: DYNC1I2

Interactor 2: ARP10 (Q9NZ32)
Actin-related protein 10 (Actin-related protein 11) (hARP11)
Gene: ACTR10

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.62	1.00	0.789

Property	Details
Experiments	28718761, 35271311
Identification Methods	proximity labelling technology, affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	Actin~WD40
Common GO terms	GO:0005829 - cytosol
Homologous interactions	7

Homologous interactions

Color coding for hit scores

	1 638 Hs			1 417
+	Hs
		148115 DC1I1_HUMAN (1-638): 2.67e-129: 396: 75.04		ARP10_HUMAN (1-417): 0: 565: 100.00
+	Hs
		929848 DC1I2_HUMAN (1-638): 3.3e-143: 432: 100.00		ACTG_HUMAN (10-384): 2.53e-173: 491: 24.44
+	Hs
		891660 WDR5_HUMAN (112-459): 1.1e-36: 141: 10.11		ACTB_HUMAN (10-384): 1.71e-173: 491: 23.94
+	Hs
		903110 WDR5_HUMAN (112-459): 1.1e-36: 141: 10.11		ACTG_HUMAN (10-384): 2.53e-173: 491: 24.44
+	Hs
		792947 LIS1_HUMAN (472-631): 9.12e-32: 129: 16.88		ACTB_HUMAN (10-384): 1.71e-173: 491: 23.94
+	Hs
		792968 LIS1_HUMAN (472-631): 9.12e-32: 129: 16.88		ACTG_HUMAN (10-384): 2.53e-173: 491: 24.44
+	Hs
		932185 RBBP7_HUMAN (429-613): 3.4e-25: 110: 17.41		ACTC_HUMAN (7-384): 4e-172: 487: 24.51