Interactor 1: ORC1 (Q13415)
Origin recognition complex subunit 1 (Replication control protein 1)
Gene: ORC1

Interactor 2: CDC6 (Q99741)
Cell division control protein 6 homolog (CDC6-related protein) (Cdc18-related protein) (HsCdc18) (p62(cdc6)) (HsCDC6)
Gene: CDC6

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.77 1.00 0.882

The method score is based on:

Property Details
Experiments 12614612, 9566895, 15232106
Identification Methods two hybrid, affinity chromatography technology, pull down, protein array
Interaction Type direct interaction, physical association

The annotation score is based on:

Property Details
Interacting Pfam domains AAA~AAA_22, AAA~AAA_lid_10, AAA~Cdc6_C, AAA_lid_10~Cdc6_C, Cdc6_C~Cdc6_C
Common GO terms GO:0003688 - DNA replication origin binding
GO:0005524 - ATP binding
GO:0005634 - nucleus
GO:0005654 - nucleoplasm
GO:0005829 - cytosol
and 3 others

more...

Homologous interactions 15

Homologous interactions

Color coding for hit scores

1 861
Hs

1 560
+ Hs
+ Hs
+ Hs
+ Dm
+ Dm
+ Sp
+ Sc
+ Sp
+ Sp
+ Sp
+ Sc
+ Sp
+ Dm
+ Sc
+ At

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024