Interactor 1: ORC2 (Q13416)
Origin recognition complex subunit 2
Gene: ORC2

Interactor 2: CDC6 (Q99741)
Cell division control protein 6 homolog (CDC6-related protein) (Cdc18-related protein) (HsCdc18) (p62(cdc6)) (HsCDC6)
Gene: CDC6

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.67 1.00 0.821

The method score is based on:

Property Details
Experiments 12614612, 15232106
Identification Methods two hybrid, affinity chromatography technology, pull down, protein array
Interaction Type direct interaction, physical association

The annotation score is based on:

Property Details
Interacting Pfam domains AAA_22~ORC2, Cdc6_C~ORC2
Common GO terms GO:0003688 - DNA replication origin binding
GO:0005634 - nucleus
GO:0005654 - nucleoplasm
GO:0006270 - DNA replication initiation
Homologous interactions 12

Homologous interactions

Color coding for hit scores

1 577
Hs

1 560
+ Hs
+ Hs
+ Dm
+ Dm
+ Sc
+ Sc
+ Dm
+ At
+ Sp
+ Sp
+ At
+ Sp

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Last updated: 15 Jul 2024