Interactor 1: ILK (Q13418)
Integrin-linked protein kinase (EC 2.7.11.1) (59 kDa serine/threonine-protein kinase) (Beta-integrin-linked kinase) (ILK-1) (ILK-2) (p59ILK)
Gene: ILK

Interactor 2: LIMS2 (Q7Z4I7)
LIM and senescent cell antigen-like-containing domain protein 2 (LIM-like protein 2) (Particularly interesting new Cys-His protein 2) (PINCH-2)
Gene: LIMS2

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.80 1.00 0.895

The method score is based on:

Property Details
Experiments 12167643, 32707033, 36736316, 23455922
Identification Methods affinity chromatography technology, pull down, tandem affinity purification
Interaction Type physical association, association

The annotation score is based on:

Property Details
Interacting Pfam domains Ank_2~LIM
Common GO terms GO:0005829 - cytosol
GO:0005886 - plasma membrane
GO:0005925 - focal adhesion
GO:0007229 - integrin-mediated signaling pathway
GO:0061351 - neural precursor cell proliferation
and 2 others

more...

Homologous interactions 20

Homologous interactions (Top 20)

Color coding for hit scores

1 452
Hs

1 341
+ Dm
+ Hs
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+ Mm
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+ Hs
+ Rn
+ Mm
+ Hs
+ Ce
+ Hs
+ Hs
+ Hs
+ Mm
+ Hs
+ Ce
+ Hs
+ Hs
+ Hs
+ Hs

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024