HitPredict

Interactor 1: ILK (Q13418)
Integrin-linked protein kinase (EC 2.7.11.1) (59 kDa serine/threonine-protein kinase) (Beta-integrin-linked kinase) (ILK-1) (ILK-2) (p59ILK)
Gene: ILK

Interactor 2: PDLI5 (Q96HC4)
PDZ and LIM domain protein 5 (Enigma homolog) (Enigma-like PDZ and LIM domains protein)
Gene: PDLIM5

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.47	1.00	0.691

Property	Details
Experiments	25852190
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	Ank_2~LIM
Common GO terms	GO:0005829 - cytosol GO:0016020 - membrane
Homologous interactions	18

Homologous interactions

Color coding for hit scores

	1 452 Hs			1 596
+	Mm
		223306 ILK_MOUSE (1-452): 6.16e-146: 425: 99.56		PAXI_MOUSE (98-534): 1.96e-34: 140: 13.96
+	Rn
		1146013 ILK_RAT (1-452): 6.16e-146: 425: 99.56		PAXI_RAT (136-534): 1.35e-33: 137: 14.79
+	Hs
		99488 ILK_HUMAN (1-452): 1.6e-146: 427: 100.00		F5GZ78_HUMAN (98-534): 1.04e-32: 134: 13.50
+	Hs
		823384 ILK_HUMAN (1-452): 1.6e-146: 427: 100.00		PAXI_HUMAN (98-534): 3.23e-32: 133: 13.50
+	Hs
		411822 LCK_HUMAN (167-449): 1.86e-109: 334: 21.99		AJUBA_HUMAN (79-593): 6.42e-48: 177: 15.28
+	Hs
		1033497 ILK_HUMAN (1-452): 1.6e-146: 427: 100.00		LIMS2_HUMAN (436-576): 6.85e-11: 65.9: 29.45
+	Ce
		107654 ILKH_CAEEL (1-450): 6.91e-123: 367: 56.44		G5EFG1_CAEEL (112-529): 1.93e-29: 125: 15.68
+	Hs
		816240 ILK_HUMAN (1-452): 1.6e-146: 427: 100.00		LIMS1_HUMAN (436-573): 4.46e-10: 63.2: 29.37
+	Mm
		223311 ILK_MOUSE (1-452): 6.16e-146: 425: 99.56		LIMS1_MOUSE (436-573): 4.63e-10: 63.2: 29.37
+	Hs
		411641 LCK_HUMAN (167-449): 1.86e-109: 334: 21.99		PAXI_HUMAN (98-534): 3.23e-32: 133: 13.50
+	Ce
		839881 ILKH_CAEEL (1-450): 6.91e-123: 367: 56.44		UNC97_CAEEL (419-573): 1.47e-15: 80.1: 30.86
+	Mm
		403454 SRC_MOUSE (173-448): 1.69e-97: 304: 24.21		PAXI_MOUSE (98-534): 1.96e-34: 140: 13.96
+	Hs
		522857 SRC_HUMAN (173-448): 1.71e-98: 307: 24.56		PAXI_HUMAN (98-534): 3.23e-32: 133: 13.50
+	Hs
		433288 YES_HUMAN (176-448): 5.77e-98: 305: 26.60		PAXI_HUMAN (98-534): 3.23e-32: 133: 13.50
+	Hs
		254384 SRC_HUMAN (173-448): 1.71e-98: 307: 24.56		LDB3_HUMAN (3-429): 6.32e-28: 121: 24.94
+	Hs
		111447 J3QRU1_HUMAN (176-448): 6.61e-98: 305: 26.60		PDLI7_HUMAN (475-594): 1.12e-28: 121: 28.33
+	Hs
		433484 YES_HUMAN (176-448): 5.77e-98: 305: 26.60		PDLI7_HUMAN (475-594): 1.12e-28: 121: 28.33
+	Hs
		523001 SRC_HUMAN (173-448): 1.71e-98: 307: 24.56		TRIP6_HUMAN (99-542): 4.54e-22: 101: 14.71