HitPredict

Interactor 1: ILK (Q13418)
Integrin-linked protein kinase (EC 2.7.11.1) (59 kDa serine/threonine-protein kinase) (Beta-integrin-linked kinase) (ILK-1) (ILK-2) (p59ILK)
Gene: ILK

Interactor 2: CAB45 (Q9BRK5)
45 kDa calcium-binding protein (Cab45) (Stromal cell-derived factor 4) (SDF-4)
Gene: SDF4

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.75	1.00	0.871

Property	Details
Experiments	25852190, 32707033, 23455922
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation, pull down, tandem affinity purification
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	Ank_2~EF-hand_7
Common GO terms	GO:0005886 - plasma membrane GO:0016020 - membrane
Homologous interactions	16

Homologous interactions

Color coding for hit scores

	1 452 Hs			1 362
+	Hs
		216226 ILK_HUMAN (1-452): 1.6e-146: 427: 100.00		CALU_HUMAN (31-362): 1.11e-61: 201: 24.55
+	Hs
		1033476 ILK_HUMAN (1-452): 1.6e-146: 427: 100.00		RCN1_HUMAN (48-360): 5.58e-55: 185: 23.96
+	Hs
		1033462 ILK_HUMAN (1-452): 1.6e-146: 427: 100.00		RCN2_HUMAN (71-362): 5.65e-53: 179: 24.23
+	At
		626359 Q8LPR4_ARATH (72-452): 1.45e-123: 387: 17.92		CML12_ARATH (189-348): 1.23e-36: 136: 16.07
+	At
		626365 BHP_ARATH (33-449): 1.99e-119: 358: 23.26		CML12_ARATH (189-348): 1.23e-36: 136: 16.07
+	At
		886573 Q8LPR4_ARATH (72-452): 1.45e-123: 387: 17.92		CALM7_ARATH (273-362): 8.01e-17: 78.5: 24.44
+	At
		99092 F4K946_ARATH (72-452): 1.43e-123: 387: 17.92		CALM7_ARATH (273-362): 8.01e-17: 78.5: 24.44
+	At
		976645 Q8LPR4_ARATH (72-452): 1.45e-123: 387: 17.92		CALM6_ARATH (273-362): 9.4e-17: 78.1: 24.44
+	At
		99093 F4K946_ARATH (72-452): 1.43e-123: 387: 17.92		CALM6_ARATH (273-362): 9.4e-17: 78.1: 24.44
+	At
		483117 BHP_ARATH (33-449): 1.99e-119: 358: 23.26		CALM4_ARATH (273-362): 4.67e-17: 78.9: 24.44
+	At
		886581 BHP_ARATH (33-449): 1.99e-119: 358: 23.26		CALM7_ARATH (273-362): 8.01e-17: 78.5: 24.44
+	At
		976652 BHP_ARATH (33-449): 1.99e-119: 358: 23.26		CALM6_ARATH (273-362): 9.4e-17: 78.1: 24.44
+	At
		222134 PBL3_ARATH (111-449): 3.77e-116: 348: 16.89		CALM4_ARATH (273-362): 4.67e-17: 78.9: 24.44
+	At
		483118 Q93ZU3_ARATH (162-452): 3.97e-109: 340: 25.59		CALM4_ARATH (273-362): 4.67e-17: 78.9: 24.44
+	At
		886613 Q9LUI6_ARATH (142-449): 2.96e-111: 334: 22.39		CALM7_ARATH (273-362): 8.01e-17: 78.5: 24.44
+	At
		976677 Q9LUI6_ARATH (142-449): 2.96e-111: 334: 22.39		CALM6_ARATH (273-362): 9.4e-17: 78.1: 24.44