Interactor 1: ILK (Q13418)
Integrin-linked protein kinase (EC 2.7.11.1) (59 kDa serine/threonine-protein kinase) (Beta-integrin-linked kinase) (ILK-1) (ILK-2) (p59ILK)
Gene: ILK

Interactor 2: PARVB (Q9HBI1)
Beta-parvin (Affixin)
Gene: PARVB

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.95 1.00 0.977

The method score is based on:

Property Details
Experiments 11402068, 26496610, 28514442, 17353931, 33961781, 35271311, 32707033, 23455922
Identification Methods affinity chromatography technology, two hybrid, enzymatic study, anti bait coimmunoprecipitation, anti tag coimmunoprecipitation, pull down, tandem affinity purification
Interaction Type physical association, direct interaction, association

The annotation score is based on:

Property Details
Interacting Pfam domains CH~PK_Tyr_Ser-Thr
Common GO terms GO:0005829 - cytosol
GO:0005886 - plasma membrane
GO:0005925 - focal adhesion
GO:0030027 - lamellipodium
GO:0034446 - substrate adhesion-dependent cell spreading
Homologous interactions 6

Homologous interactions

Color coding for hit scores

1 452
Hs

1 364
+ Mm
+ Mm
+ Hs
+ Dm
+ Hs
+ Ce

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024