HitPredict

Interactor 1: IKZF1 (Q13422)
DNA-binding protein Ikaros (Ikaros family zinc finger protein 1) (Lymphoid transcription factor LyF-1)
Gene: IKZF1

Interactor 2: LHX4 (Q969G2)
LIM/homeobox protein Lhx4 (LIM homeobox protein 4)
Gene: LHX4

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.481

Property	Details
Experiments	26871637
Identification Methods	two hybrid
Interaction Type	direct interaction

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0006357 - regulation of transcription by RNA polymerase II
Homologous interactions	18

Homologous interactions

Color coding for hit scores

	1 519 Hs			1 390
+	Hs
		3368 IKZF1_HUMAN (1-519): 0: 664: 100.00		A0A0S2Z5S9_HUMAN (1-88): 2.21e-57: 184: 97.73
+	Hs
		1033682 IKZF1_HUMAN (1-519): 0: 664: 100.00		LMO3_HUMAN (19-158): 3.93e-52: 172: 37.67
+	Hs
		903710 IKZF1_HUMAN (1-519): 0: 664: 100.00		LMO4_HUMAN (29-150): 2.22e-31: 118: 43.31
+	Hs
		638501 IKZF1_HUMAN (1-519): 0: 664: 100.00		RBTN1_HUMAN (89-189): 8.78e-11: 61.9: 16.83
+	Hs
		846679 ZNF84_HUMAN (86-518): 3.19e-150: 449: 13.75		LMO3_HUMAN (19-158): 3.93e-52: 172: 37.67
+	Hs
		855972 ZN135_HUMAN (2-456): 3.86e-154: 456: 15.70		LMO4_HUMAN (29-150): 2.22e-31: 118: 43.31
+	Hs
		903791 IKZF3_HUMAN (11-515): 4.42e-139: 413: 53.82		LMO4_HUMAN (29-150): 2.22e-31: 118: 43.31
+	Hs
		301019 IKZF3_HUMAN (11-515): 4.42e-139: 413: 53.82		ABLM3_HUMAN (30-193): 1.92e-23: 104: 21.77
+	Hs
		638487 ZNF84_HUMAN (86-518): 3.19e-150: 449: 13.75		RBTN1_HUMAN (89-189): 8.78e-11: 61.9: 16.83
+	Hs
		638592 IKZF3_HUMAN (11-515): 4.42e-139: 413: 53.82		RBTN1_HUMAN (89-189): 8.78e-11: 61.9: 16.83
+	Hs
		1332093 IKZF5_HUMAN (62-193): 1.16e-11: 68.6: 33.33		LHX3_HUMAN (1-390): 1.94e-87: 271: 60.25
+	Hs
		822633 OZF_HUMAN (118-196): 2.3e-12: 69.7: 37.98		LHX1_HUMAN (29-389): 3.38e-61: 204: 32.13
+	Hs
		1251439 ZIM3_HUMAN (118-224): 2.19e-14: 77.4: 33.65		LMO3_HUMAN (19-158): 3.93e-52: 172: 37.67
+	Dm
		114398 CF2_DROME (117-191): 1.44e-10: 65.5: 41.33		M9PCA3_DROME (28-360): 2.75e-47: 172: 28.65
+	Dm
		592803 CF2_DROME (117-191): 1.44e-10: 65.5: 41.33		Q9VTW5_DROME (28-360): 2.46e-47: 172: 28.65
+	Hs
		1078405 ZKSC8_HUMAN (118-171): 1.71e-09: 62.4: 51.85		LMO3_HUMAN (19-158): 3.93e-52: 172: 37.67
+	Hs
		903785 RBAK_HUMAN (287-516): 2.36e-24: 109: 10.88		LMO4_HUMAN (29-150): 2.22e-31: 118: 43.31
+	Hs
		903756 ZN397_HUMAN (118-197): 2.27e-11: 68.2: 37.50		LMO4_HUMAN (29-150): 2.22e-31: 118: 43.31