HitPredict

Interactor 1: IKZF1 (Q13422)
DNA-binding protein Ikaros (Ikaros family zinc finger protein 1) (Lymphoid transcription factor LyF-1)
Gene: IKZF1

Interactor 2: MTA3 (Q9BTC8)
Metastasis-associated protein MTA3
Gene: MTA3

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.65	0.60	0.628

Property	Details
Experiments	28514442, 33961781
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0045892 - negative regulation of DNA-templated transcription GO:0046872 - metal ion binding
Homologous interactions	6

Homologous interactions

Color coding for hit scores

	1 519 Hs			1 594
+	Hs
		1031846 IKZF1_HUMAN (1-519): 0: 664: 100.00		MTA1_HUMAN (1-586): 0: 627: 69.14
+	Hs
		296013 IKZF1_HUMAN (1-519): 0: 664: 100.00		MTA2_HUMAN (1-584): 0: 611: 64.40
+	Hs
		1031971 IKZF3_HUMAN (11-515): 4.42e-139: 413: 53.82		MTA1_HUMAN (1-586): 0: 627: 69.14
+	Hs
		296171 IKZF3_HUMAN (11-515): 4.42e-139: 413: 53.82		MTA2_HUMAN (1-584): 0: 611: 64.40
+	Hs
		1033769 IKZF1_HUMAN (1-519): 0: 664: 100.00		NCOR2_HUMAN (53-566): 2.01e-95: 322: 14.10
+	Hs
		1350409 IKZF3_HUMAN (11-515): 4.42e-139: 413: 53.82		RCOR3_HUMAN (150-571): 3.76e-83: 270: 19.03