HitPredict

Interactor 1: XRCC4 (Q13426)
DNA repair protein XRCC4 (hXRCC4) (X-ray repair cross-complementing protein 4) [Cleaved into: Protein XRCC4, C-terminus (XRCC4/C)]
Gene: XRCC4

Interactor 2: APLF (Q8IW19)
Aprataxin and PNK-like factor (EC 3.1.-.-) (Apurinic-apyrimidinic endonuclease APLF) (PNK and APTX-like FHA domain-containing protein) (XRCC1-interacting protein 1)
Gene: APLF

Species: Homo sapiens

Source: mint

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.89	0.55	0.701

Property	Details
Experiments	26186194, 28514442, 33961781, 17396150, 17353262, 23178593
Identification Methods	affinity chromatography technology, pull down, two hybrid, anti tag coimmunoprecipitation, filter binding
Interaction Type	physical association, direct interaction, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0005829 - cytosol GO:0006302 - double-strand break repair GO:0006303 - double-strand break repair via nonhomologous end joining and 1 others more... GO:0035861 - site of double-strand break
Homologous interactions	0