HitPredict

Interactor 1: TCOF (Q13428)
Treacle protein (Treacher Collins syndrome protein)
Gene: TCOF1

Interactor 2: PKHA7 (Q6IQ23)
Pleckstrin homology domain-containing family A member 7 (PH domain-containing family A member 7)
Gene: PLEKHA7

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.33	0.60	0.445

Property	Details
Experiments	28877994
Identification Methods	anti bait coimmunoprecipitation
Interaction Type	association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005654 - nucleoplasm GO:0005829 - cytosol
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 1488 Hs			1 1121
+	Hs
		1034131 TCOF_HUMAN (1-1488): 2.22e-113: 394: 100.00		SMUF1_HUMAN (4-213): 3.11e-48: 187: 18.58
+	Hs
		125432 TCOF_HUMAN (1-1488): 2.22e-113: 394: 100.00		WWP2_HUMAN (8-203): 2.64e-43: 173: 24.39
+	Hs
		1154038 NIPBL_HUMAN (429-1488): 4.56e-56: 217: 10.13		NIPBL_HUMAN (210-1111): 1.78e-57: 220: 12.13
+	Hs
		965158 ANK2_HUMAN (195-1161): 9.81e-10: 65.9: 15.17		PKHA5_HUMAN (11-1074): 3.5e-95: 330: 29.45
+	Hs
		1154076 NIPBL_HUMAN (429-1488): 4.56e-56: 217: 10.13		PKHA4_HUMAN (113-465): 8.31e-38: 154: 28.84
+	Hs
		807849 MAP1B_HUMAN (41-1111): 4.34e-44: 178: 10.34		SMUF1_HUMAN (4-213): 3.11e-48: 187: 18.58
+	Hs
		1056986 MDC1_HUMAN (238-1377): 7.73e-52: 203: 12.82		PKHA4_HUMAN (113-465): 8.31e-38: 154: 28.84
+	Hs
		125817 PRC2C_HUMAN (35-1393): 5.37e-41: 168: 9.91		WWP2_HUMAN (8-203): 2.64e-43: 173: 24.39
+	Hs
		807842 MAP1B_HUMAN (41-1111): 4.34e-44: 178: 10.34		PKHA4_HUMAN (113-465): 8.31e-38: 154: 28.84
+	Hs
		1331734 PRC2C_HUMAN (35-1393): 5.37e-41: 168: 9.91		PKHA4_HUMAN (113-465): 8.31e-38: 154: 28.84
+	Hs
		1056827 MDC1_HUMAN (238-1377): 7.73e-52: 203: 12.82		MDC1_HUMAN (281-1110): 6.34e-20: 98.8: 10.84
+	Hs
		297818 K0754_HUMAN (470-1040): 1.07e-20: 102: 14.51		AFAD_HUMAN (329-1063): 1.33e-45: 182: 11.19
+	Hs
		1264807 TITIN_HUMAN (91-778): 3.15e-09: 64.2: 9.45		SMUF2_HUMAN (3-213): 6.3e-48: 185: 18.18
+	Hs
		876457 TITIN_HUMAN (91-778): 3.15e-09: 64.2: 9.45		AFAD_HUMAN (329-1063): 1.33e-45: 182: 11.19
+	Hs
		1170086 SRCAP_HUMAN (497-1303): 7.2e-11: 69.8: 13.18		PKHA4_HUMAN (113-465): 8.31e-38: 154: 28.84
+	Dm
		54898 A1ZA72_DROME (61-1471): 1e-17: 92.5: 15.45		SUDX_DROME (1-211): 5.48e-29: 127: 14.98
+	Hs
		131748 BCL9_HUMAN (2-1253): 5.07e-20: 99.3: 8.30		WWOX_HUMAN (9-115): 8.02e-20: 95.4: 29.91
+	Hs
		212310 ANK2_HUMAN (195-1161): 9.81e-10: 65.9: 15.17		CYH3_HUMAN (160-280): 1.5e-27: 118: 27.64
+	Dm
		113976 M9PB30_DROME (103-613): 2.85e-17: 91: 10.18		M9PB30_DROME (699-1115): 4.02e-09: 63.5: 9.20
+	Hs
		554367 MUC1_HUMAN (180-968): 3.18e-10: 67.4: 14.83		WWP1_HUMAN (42-252): 1.75e-13: 77.4: 17.05