HitPredict

Interactor 1: TCOF (Q13428)
Treacle protein (Treacher Collins syndrome protein)
Gene: TCOF1

Interactor 2: SIR7 (Q9NRC8)
NAD-dependent protein deacetylase sirtuin-7 (EC 2.3.1.286) (NAD-dependent protein deacylase sirtuin-7) (EC 2.3.1.-) (Regulatory protein SIR2 homolog 7) (SIR2-like protein 7)
Gene: SIRT7

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	22586326
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005654 - nucleoplasm GO:0005730 - nucleolus
Homologous interactions	8

Homologous interactions

Color coding for hit scores

	1 1488 Hs			1 400
+	Hs
		1154078 NIPBL_HUMAN (429-1488): 4.56e-56: 217: 10.13		SIR7_HUMAN (1-400): 0: 535: 100.00
+	Hs
		1056998 MDC1_HUMAN (238-1377): 7.73e-52: 203: 12.82		SIR7_HUMAN (1-400): 0: 535: 100.00
+	Hs
		807855 MAP1B_HUMAN (41-1111): 4.34e-44: 178: 10.34		SIR7_HUMAN (1-400): 0: 535: 100.00
+	Hs
		1344557 PRC2C_HUMAN (35-1393): 5.37e-41: 168: 9.91		SIR7_HUMAN (1-400): 0: 535: 100.00
+	Hs
		1034089 TCOF_HUMAN (1-1488): 2.22e-113: 394: 100.00		SIR6_HUMAN (77-368): 3.24e-100: 303: 38.87
+	Hs
		1056888 MDC1_HUMAN (238-1377): 7.73e-52: 203: 12.82		SIR6_HUMAN (77-368): 3.24e-100: 303: 38.87
+	Hs
		1170068 SRCAP_HUMAN (497-1303): 7.2e-11: 69.8: 13.18		SIR6_HUMAN (77-368): 3.24e-100: 303: 38.87
+	Mm
		1265847 NCOR2_MOUSE (274-1478): 5.19e-11: 70: 9.69		SIR1_MOUSE (78-380): 5.54e-78: 256: 19.94