HitPredict

Interactor 1: G4S034 (G4S034)
Spectrin alpha chain
Gene: spc-1

Interactor 2: G5EFG1 (G5EFG1)
PDZ and LIM domain protein Zasp
Gene: alp-1

Species: Caenorhabditis elegans

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.481

Property	Details
Experiments	31462781
Identification Methods	two hybrid
Interaction Type	direct interaction

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0030036 - actin cytoskeleton organization
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 2427 Ce			1 684
+	Ce
		104744 G5EC35_CAEEL (2-2392): 8.84e-61: 235: 15.61		G5EFG1_CAEEL (1-684): 1.39e-152: 459: 100.00
+	Ce
		103987 G5EBH3_CAEEL (2-2392): 8.32e-61: 235: 15.61		G5EC72_CAEEL (1-397): 1.9e-72: 242: 100.00
+	Hs
		211672 ACTN4_HUMAN (1940-2425): 1.45e-72: 265: 33.13		PDLI7_HUMAN (195-622): 1.11e-25: 112: 13.95
+	Mm
		513820 DMD_MOUSE (1398-2390): 4.95e-19: 97.4: 12.27		LDB3_MOUSE (15-684): 8.1e-83: 278: 22.04
+	Mm
		1186636 ACTN1_MOUSE (1288-1533): 2.99e-09: 64.7: 23.53		PDLI5_MOUSE (15-684): 1.31e-89: 293: 22.11
+	Hs
		823397 GOGB1_HUMAN (1558-2419): 2.25e-21: 105: 8.05		PAXI_HUMAN (125-683): 7.7e-69: 237: 18.75
+	Mm
		1337461 ACTN2_MOUSE (1057-1347): 6.87e-09: 63.5: 22.64		LDB3_MOUSE (15-684): 8.1e-83: 278: 22.04
+	Hs
		1045539 SPTN1_HUMAN (4-1743): 7.39e-59: 228: 20.85		PDLI7_HUMAN (195-622): 1.11e-25: 112: 13.95
+	Hs
		254383 ACTN1_HUMAN (1288-1533): 8.27e-09: 63.2: 23.16		LDB3_HUMAN (15-684): 8.88e-80: 270: 22.19
+	Hs
		254385 ACTN2_HUMAN (1057-1364): 7.93e-09: 63.2: 22.09		LDB3_HUMAN (15-684): 8.88e-80: 270: 22.19
+	Hs
		117234 ACTN4_HUMAN (1940-2425): 1.45e-72: 265: 33.13		PDLI1_HUMAN (629-684): 1.74e-11: 68: 26.79
+	Hs
		823516 MACF1_HUMAN (838-2392): 1.77e-14: 82.3: 8.49		PAXI_HUMAN (125-683): 7.7e-69: 237: 18.75
+	Dm
		54833 ACTN_DROME (1092-1377): 7.9e-09: 63.5: 21.41		ZASP_DROME (273-684): 9.4e-60: 220: 31.80
+	Hs
		522595 MYH7_HUMAN (681-1773): 3.9e-33: 143: 9.15		LIMS1_HUMAN (509-621): 2.42e-12: 70.5: 33.33
+	Hs
		963432 SPTB2_HUMAN (1693-2399): 1.01e-15: 86.6: 18.23		PDLI7_HUMAN (195-622): 1.11e-25: 112: 13.95
+	Hs
		506846 SPTB1_HUMAN (1693-2416): 4.23e-11: 71.2: 18.43		PDLI7_HUMAN (195-622): 1.11e-25: 112: 13.95
+	Hs
		725704 ACTN2_HUMAN (1057-1364): 7.93e-09: 63.2: 22.09		PDLI7_HUMAN (195-622): 1.11e-25: 112: 13.95
+	Hs
		117245 ACTN1_HUMAN (1288-1533): 8.27e-09: 63.2: 23.16		PDLI1_HUMAN (629-684): 1.74e-11: 68: 26.79
+	Hs
		117257 ACTN2_HUMAN (1057-1364): 7.93e-09: 63.2: 22.09		PDLI1_HUMAN (629-684): 1.74e-11: 68: 26.79
+	Hs
		521502 ACTN1_HUMAN (1288-1533): 8.27e-09: 63.2: 23.16		PDLI4_HUMAN (567-622): 5.16e-10: 63.4: 26.79