HitPredict

Interactor 1: SF3B2 (Q13435)
Splicing factor 3B subunit 2 (Pre-mRNA-splicing factor SF3b 145 kDa subunit) (SF3b145) (Spliceosome-associated protein 145) (SAP 145)
Gene: SF3B2

Interactor 2: RBM7 (Q9Y580)
RNA-binding protein 7 (RNA-binding motif protein 7)
Gene: RBM7

Species: Homo sapiens

Source: mint

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.90	1.00	0.951

Property	Details
Experiments	22365833, 26186194, 28514442, 12634307, 33961781, 27905398
Identification Methods	two hybrid, affinity chromatography technology, pull down, anti tag coimmunoprecipitation
Interaction Type	direct interaction, physical association, association

Property	Details
Interacting Pfam domains	PSP~RRM_1
Common GO terms	GO:0003723 - RNA binding GO:0005634 - nucleus GO:0005654 - nucleoplasm
Homologous interactions	7

Homologous interactions

Color coding for hit scores

	1 895 Hs			1 266
+	Hs
		882908 SF3B2_HUMAN (1-895): 0: 1129: 100.00		RBM11_HUMAN (1-99): 7.78e-39: 138: 60.61
+	Hs
		1034292 SF3B2_HUMAN (1-895): 0: 1129: 100.00		SF3B4_HUMAN (7-242): 3.59e-15: 76.6: 15.39
+	Hs
		92678 E9PPJ0_HUMAN (1-895): 0: 1094: 98.10		SF3B4_HUMAN (7-242): 3.59e-15: 76.6: 15.39
+	Dm
		1372645 Q9VQK7_DROME (278-895): 0: 687: 57.90		Q9W424_DROME (7-93): 8e-11: 63.2: 33.71
+	Sc
		376903 CUS1_YEAST (326-754): 2.32e-111: 350: 26.77		PABP_YEAST (10-258): 4.72e-37: 139: 15.22
+	Sc
		971709 CUS1_YEAST (326-754): 2.32e-111: 350: 26.77		HSH49_YEAST (5-107): 1.12e-32: 120: 32.14
+	Pf
		1212910 Q8IKL7_PLAF7 (351-728): 2.06e-122: 387: 38.16		Q8ILQ0_PLAF7 (7-106): 8.07e-10: 60.5: 21.00