HitPredict

Interactor 1: OS9 (Q13438)
Protein OS-9 (Amplified in osteosarcoma 9)
Gene: OS9

Interactor 2: EDEM3 (Q9BZQ6)
ER degradation-enhancing alpha-mannosidase-like protein 3 (EC 3.2.1.113) (Alpha-1,2-mannosidase EDEM3)
Gene: EDEM3

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.62	0.60	0.611

Property	Details
Experiments	28514442, 28366632
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005783 - endoplasmic reticulum GO:0005788 - endoplasmic reticulum lumen GO:0036503 - ERAD pathway
Homologous interactions	4

Homologous interactions

Color coding for hit scores

	1 667 Hs			1 932
+	Hs
		1034525 OS9_HUMAN (1-667): 0: 993: 100.00		EDEM2_HUMAN (19-535): 0: 618: 37.62
+	Hs
		1034504 OS9_HUMAN (1-667): 0: 993: 100.00		EDEM1_HUMAN (43-514): 0: 605: 42.42
+	Hs
		1288814 ERLEC_HUMAN (29-229): 1.88e-27: 118: 24.41		EDEM3_HUMAN (1-932): 0: 1458: 100.00
+	Hs
		1267987 ERLEC_HUMAN (29-229): 1.88e-27: 118: 24.41		EDEM1_HUMAN (43-514): 0: 605: 42.42