HitPredict

Interactor 1: G4SFM6 (G4SFM6)
Ral guanine nucleotide dissociation stimulator-like 1
Gene: rgl-1

Interactor 2: LET60 (P22981)
Ras protein let-60 (Abnormal cell lineage protein 34) (Lethal protein 60)
Gene: let-60

Species: Caenorhabditis elegans

Source: biogrid

Category: High-throughput

Confidence: High

Method score Annotation score Interaction score
0.68 1.00 0.825

The method score is based on:

Property Details
Experiments 12679813, 10615043, 14704431
Identification Methods two hybrid
Interaction Type direct interaction

The annotation score is based on:

Property Details
Interacting Pfam domains RA~Ras, Ras~RasGEF, Ras~RasGEF_N
Common GO terms GO:0005886 - plasma membrane
GO:0007173 - epidermal growth factor receptor signaling pathway
GO:0007265 - Ras protein signal transduction
GO:0040026 - positive regulation of vulval development
Homologous interactions 20

Homologous interactions (Top 20)

Color coding for hit scores

1 860
Ce

1 184
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+ Sc
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+ Mm

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Last updated: 15 Jul 2024