HitPredict

Interactor 1: ADA15 (Q13444)
Disintegrin and metalloproteinase domain-containing protein 15 (ADAM 15) (EC 3.4.24.-) (Metalloprotease RGD disintegrin protein) (Metalloproteinase-like, disintegrin-like, and cysteine-rich protein 15) (MDC-15) (Metargidin)
Gene: ADAM15

Interactor 2: PTK6 (Q13882)
Protein-tyrosine kinase 6 (EC 2.7.10.2) (Breast tumor kinase) (Tyrosine-protein kinase BRK)
Gene: PTK6

Species: Homo sapiens

Source: innatedb

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.44	0.60	0.515

Property	Details
Experiments	18296648
Identification Methods	affinity chromatography technology, pull down
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005886 - plasma membrane GO:0045087 - innate immune response
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 863 Hs			1 451
+	Hs
		412180 ADA15_HUMAN (1-863): 0: 556: 100.00		FYN_HUMAN (10-450): 0: 521: 42.35
+	Hs
		522964 ADA15_HUMAN (1-863): 0: 556: 100.00		SRC_HUMAN (3-450): 0: 521: 43.30
+	Hs
		433344 ADA15_HUMAN (1-863): 0: 556: 100.00		YES_HUMAN (10-450): 0: 519: 42.86
+	Hs
		411708 ADA15_HUMAN (1-863): 0: 556: 100.00		LCK_HUMAN (3-449): 0: 517: 39.07
+	Hs
		442824 ADA15_HUMAN (1-863): 0: 556: 100.00		HCK_HUMAN (4-449): 8.95e-179: 511: 39.82
+	Hs
		337463 ADA15_HUMAN (1-863): 0: 556: 100.00		ABL1_HUMAN (1-449): 2.48e-170: 509: 35.17
+	Hs
		433748 ADA15_HUMAN (1-863): 0: 556: 100.00		LYN_HUMAN (3-449): 5.02e-177: 506: 38.19
+	Hs
		197579 ADA12_HUMAN (42-856): 8.46e-167: 509: 35.32		FYN_HUMAN (10-450): 0: 521: 42.35
+	Hs
		197583 ADA12_HUMAN (42-856): 8.46e-167: 509: 35.32		SRC_HUMAN (3-450): 0: 521: 43.30
+	Hs
		523142 ADA19_HUMAN (8-859): 3.95e-164: 504: 33.00		SRC_HUMAN (3-450): 0: 521: 43.30
+	Hs
		197581 ADA12_HUMAN (42-856): 8.46e-167: 509: 35.32		HCK_HUMAN (4-449): 8.95e-179: 511: 39.82
+	Hs
		433747 ADAM9_HUMAN (31-823): 4.3e-168: 510: 31.00		LYN_HUMAN (3-449): 5.02e-177: 506: 38.19
+	Hs
		197580 ADA12_HUMAN (42-856): 8.46e-167: 509: 35.32		LYN_HUMAN (3-449): 5.02e-177: 506: 38.19
+	Hs
		442882 ADA19_HUMAN (8-859): 3.95e-164: 504: 33.00		HCK_HUMAN (4-449): 8.95e-179: 511: 39.82
+	Hs
		433995 ADA19_HUMAN (8-859): 3.95e-164: 504: 33.00		LYN_HUMAN (3-449): 5.02e-177: 506: 38.19
+	Hs
		522899 ADAM8_HUMAN (1-851): 5.57e-160: 489: 31.26		SRC_HUMAN (3-450): 0: 521: 43.30
+	Hs
		996560 ADA15_HUMAN (1-863): 0: 556: 100.00		ITK_HUMAN (7-447): 1.9e-152: 448: 32.82
+	Hs
		442890 ADA22_HUMAN (7-698): 1.49e-136: 430: 27.98		HCK_HUMAN (4-449): 8.95e-179: 511: 39.82
+	Hs
		434044 ADA22_HUMAN (7-698): 1.49e-136: 430: 27.98		LYN_HUMAN (3-449): 5.02e-177: 506: 38.19
+	Hs
		152218 ADA10_HUMAN (69-525): 5.98e-94: 313: 23.44		ABL1_HUMAN (1-449): 2.48e-170: 509: 35.17