HitPredict

Interactor 1: ADA15 (Q13444)
Disintegrin and metalloproteinase domain-containing protein 15 (ADAM 15) (EC 3.4.24.-) (Metalloprotease RGD disintegrin protein) (Metalloproteinase-like, disintegrin-like, and cysteine-rich protein 15) (MDC-15) (Metargidin)
Gene: ADAM15

Interactor 2: SH3R1 (Q7Z6J0)
E3 ubiquitin-protein ligase SH3RF1 (EC 2.3.2.27) (Plenty of SH3s) (Protein POSH) (RING finger protein 142) (RING-type E3 ubiquitin transferase SH3RF1) (SH3 domain-containing RING finger protein 1) (SH3 multiple domains protein 2)
Gene: SH3RF1

Species: Homo sapiens

Source: mint

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	16374509
Identification Methods	filter binding
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0046872 - metal ion binding
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 863 Hs			1 888
+	Hs
		788990 ADA15_HUMAN (1-863): 0: 556: 100.00		TEC_HUMAN (14-331): 2.16e-33: 139: 13.54
+	Hs
		298978 ADA15_HUMAN (1-863): 0: 556: 100.00		SRBS2_HUMAN (428-502): 2.43e-22: 105: 44.32
+	Hs
		788989 ADAM9_HUMAN (31-823): 4.3e-168: 510: 31.00		TEC_HUMAN (14-331): 2.16e-33: 139: 13.54
+	Hs
		789007 ADA19_HUMAN (8-859): 3.95e-164: 504: 33.00		TEC_HUMAN (14-331): 2.16e-33: 139: 13.54
+	Hs
		1034750 ADA15_HUMAN (1-863): 0: 556: 100.00		ARHG7_HUMAN (725-888): 1.36e-14: 80.3: 19.88
+	Hs
		1034771 ADA15_HUMAN (1-863): 0: 556: 100.00		SRBS1_HUMAN (125-416): 3.54e-14: 79.3: 19.54
+	Hs
		1034770 ADA15_HUMAN (1-863): 0: 556: 100.00		SH3G2_HUMAN (371-504): 2.89e-14: 77.2: 17.91
+	Hs
		1034753 ADA15_HUMAN (1-863): 0: 556: 100.00		ITSN1_HUMAN (551-888): 1.75e-12: 73.7: 12.83
+	Hs
		788983 ADAM8_HUMAN (1-851): 5.57e-160: 489: 31.26		TEC_HUMAN (14-331): 2.16e-33: 139: 13.54
+	Hs
		1034763 ADA15_HUMAN (1-863): 0: 556: 100.00		SH3R3_HUMAN (691-888): 1.88e-10: 66.8: 20.71
+	Hs
		298977 ADAM9_HUMAN (31-823): 4.3e-168: 510: 31.00		SRBS2_HUMAN (428-502): 2.43e-22: 105: 44.32
+	Mm
		1142116 ADAM9_MOUSE (1-832): 1.79e-174: 527: 31.47		SH3G2_MOUSE (371-504): 1.82e-14: 78: 18.66
+	Hs
		197624 ADA12_HUMAN (42-856): 8.46e-167: 509: 35.32		ITSN2_HUMAN (117-266): 1.18e-14: 81: 18.99
+	Hs
		1034723 ADAM9_HUMAN (31-823): 4.3e-168: 510: 31.00		SH3G2_HUMAN (371-504): 2.89e-14: 77.2: 17.91
+	Mm
		292357 ADA15_MOUSE (1-844): 1.51e-166: 507: 79.67		SH3G2_MOUSE (371-504): 1.82e-14: 78: 18.66
+	Hs
		197604 ADA12_HUMAN (42-856): 8.46e-167: 509: 35.32		SH319_HUMAN (133-192): 4.35e-13: 75.4: 40.00
+	Hs
		197601 ADA12_HUMAN (42-856): 8.46e-167: 509: 35.32		ITSN1_HUMAN (551-888): 1.75e-12: 73.7: 12.83
+	Hs
		1307433 ADA19_HUMAN (8-859): 3.95e-164: 504: 33.00		SH3G2_HUMAN (371-504): 2.89e-14: 77.2: 17.91
+	Hs
		152209 ADA10_HUMAN (69-525): 5.98e-94: 313: 23.44		VINEX_HUMAN (245-888): 2.14e-32: 136: 13.37
+	Hs
		152212 ADA10_HUMAN (69-525): 5.98e-94: 313: 23.44		GRAP2_HUMAN (835-887): 3.61e-12: 70.6: 28.30