HitPredict

Interactor 1: LSAMP (Q13449)
Limbic system-associated membrane protein (LSAMP) (IgLON family member 3)
Gene: LSAMP

Interactor 2: NEGR1 (Q7Z3B1)
Neuronal growth regulator 1 (IgLON family member 4)
Gene: NEGR1

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.52	1.00	0.724

Property	Details
Experiments	21982860
Identification Methods	pull down, protein array
Interaction Type	direct interaction, physical association

Property	Details
Interacting Pfam domains	Ig_3~I-set, I-set~V-set, Ig_3~Ig_3, Ig_3~V-set
Common GO terms	GO:0005576 - extracellular region GO:0005886 - plasma membrane GO:0098552 - side of membrane
Homologous interactions	19

Homologous interactions

Color coding for hit scores

	1 338 Hs			1 354
+	Dm
		1370925 Q9VMN6_DROME (119-334): 1.44e-23: 103: 18.38		Q9VMN6_DROME (30-313): 1.99e-78: 253: 28.95
+	Dm
		547970 AMAL_DROME (9-307): 2.87e-74: 234: 28.40		AMAL_DROME (53-312): 2.89e-26: 108: 30.18
+	Dm
		1097652 LACH_DROME (90-306): 1.4e-25: 107: 33.04		LACH_DROME (16-342): 3.72e-68: 219: 27.20
+	Dm
		1363147 Q9VCT4_DROME (21-312): 3.34e-66: 219: 26.42		Q9VCT4_DROME (119-351): 1.2e-22: 100: 16.67
+	Hs
		1034838 LSAMP_HUMAN (1-323): 1.55e-74: 235: 100.00		NTRI_HUMAN (1-133): 1.38e-14: 75.6: 14.18
+	Hs
		1061308 OPCM_HUMAN (9-332): 9.99e-75: 235: 55.18		NTRI_HUMAN (1-133): 1.38e-14: 75.6: 14.18
+	Dr
		46931 A4JYK9_DANRE (25-335): 5.55e-63: 205: 48.40		A0A4W4_DANRE (161-349): 6.06e-25: 105: 15.82
+	Hs
		530171 OPCM_HUMAN (9-332): 9.99e-75: 235: 55.18		NCAM1_HUMAN (90-312): 5.9e-13: 72: 24.69
+	Dr
		60051 A4JYK9_DANRE (25-335): 5.55e-63: 205: 48.40		B7ZV58_DANRE (147-350): 7.92e-23: 99.1: 14.16
+	Hs
		1034819 LSAMP_HUMAN (1-323): 1.55e-74: 235: 100.00		LSAMP_HUMAN (3-130): 7.61e-12: 67.5: 13.18
+	Dm
		219801 O44924_DROME (22-336): 1.24e-53: 191: 18.98		O44924_DROME (1-174): 6.45e-19: 90.2: 15.93
+	Rn
		222935 DCC_RAT (1-319): 5.89e-21: 96.1: 12.68		ROBO1_RAT (1-350): 2.54e-38: 147: 15.17
+	Ce
		103933 SAX3_CAEEL (1-304): 1.96e-36: 141: 16.52		SAX3_CAEEL (1-209): 5.97e-21: 96.4: 14.52
+	Mm
		1142535 CNTN2_MOUSE (147-335): 5.2e-22: 99.2: 16.59		CNTN2_MOUSE (154-353): 2.67e-26: 112: 16.81
+	Dr
		46930 A0A4W4_DANRE (4-239): 1.44e-23: 101: 16.80		A0A4W4_DANRE (161-349): 6.06e-25: 105: 15.82
+	Dr
		46932 A0A4W4_DANRE (4-239): 1.44e-23: 101: 16.80		B7ZV58_DANRE (147-350): 7.92e-23: 99.1: 14.16
+	Dr
		46933 A0A4W4_DANRE (4-239): 1.44e-23: 101: 16.80		Q642G9_DANRE (2-218): 3.3e-21: 94.9: 11.40
+	Dm
		1370928 Q9VMN9_DROME (127-334): 1.39e-27: 113: 20.61		Q9VMN9_DROME (211-349): 1.14e-10: 64.4: 14.74
+	Mm
		530206 CNTN2_MOUSE (147-335): 5.2e-22: 99.2: 16.59		NCAM1_MOUSE (103-312): 1.39e-14: 77: 26.50