HitPredict

Interactor 1: FKBP5 (Q13451)
Peptidyl-prolyl cis-trans isomerase FKBP5 (PPIase FKBP5) (EC 5.2.1.8) (51 kDa FK506-binding protein) (51 kDa FKBP) (FKBP-51) (54 kDa progesterone receptor-associated immunophilin) (Androgen-regulated protein 6) (FF1 antigen) (FK506-binding protein 5) (FKBP-5) (FKBP54) (p54) (HSP90-binding immunophilin) (Rotamase)
Gene: FKBP5

Interactor 2: PHLP2 (Q6ZVD8)
PH domain leucine-rich repeat-containing protein phosphatase 2 (EC 3.1.3.16) (PH domain leucine-rich repeat-containing protein phosphatase-like) (PHLPP-like)
Gene: PHLPP2

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	28363942
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005654 - nucleoplasm GO:0005737 - cytoplasm GO:0005829 - cytosol
Homologous interactions	7

Homologous interactions

Color coding for hit scores

	1 457 Hs			1 1323
+	Hs
		232865 FKBP5_HUMAN (1-457): 6.63e-145: 423: 100.00		PHLP1_HUMAN (36-1300): 0: 845: 53.04
+	Hs
		232852 FKBP4_HUMAN (1-456): 1.79e-136: 402: 54.59		PHLP1_HUMAN (36-1300): 0: 845: 53.04
+	Hs
		118649 AIP_HUMAN (144-414): 1.52e-49: 173: 16.72		PHLP1_HUMAN (36-1300): 0: 845: 53.04
+	Hs
		1035000 FKBP5_HUMAN (1-457): 6.63e-145: 423: 100.00		LRC40_HUMAN (249-701): 1.53e-22: 105: 27.03
+	At
		1341059 FK201_ARATH (22-135): 1.12e-22: 96.7: 47.01		BRL2_ARATH (493-948): 7e-49: 192: 14.43
+	Hs
		685036 STIP1_HUMAN (265-457): 3.91e-23: 104: 17.62		LRC40_HUMAN (249-701): 1.53e-22: 105: 27.03
+	Hs
		684709 STIP1_HUMAN (265-457): 3.91e-23: 104: 17.62		SCRIB_HUMAN (438-732): 2.62e-12: 73.9: 29.00