HitPredict

Interactor 1: FKBP5 (Q13451)
Peptidyl-prolyl cis-trans isomerase FKBP5 (PPIase FKBP5) (EC 5.2.1.8) (51 kDa FK506-binding protein) (51 kDa FKBP) (FKBP-51) (54 kDa progesterone receptor-associated immunophilin) (Androgen-regulated protein 6) (FF1 antigen) (FK506-binding protein 5) (FKBP-5) (FKBP54) (p54) (HSP90-binding immunophilin) (Rotamase)
Gene: FKBP5

Interactor 2: Q86SX1 (Q86SX1)
Full-length cDNA 5-PRIME end of clone CS0DN005YI08 of Adult brain of Homo sapiens (human)
Gene: Q86SX1

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.33	0.60	0.445

Property	Details
Experiments	25036637
Identification Methods	anti tag coimmunoprecipitation
Interaction Type	association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005829 - cytosol
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 457 Hs			1 262
+	Hs
		972539 FKBP4_HUMAN (1-456): 1.79e-136: 402: 54.59		Q86SX1_HUMAN (1-262): 0: 505: 100.00
+	Hs
		111937 FKBP5_HUMAN (1-457): 6.63e-145: 423: 100.00		K9JA46_HUMAN (123-262): 1.08e-84: 269: 100.00
+	Hs
		431818 FKBP5_HUMAN (1-457): 6.63e-145: 423: 100.00		HS90A_HUMAN (123-262): 1.08e-84: 269: 100.00
+	Hs
		1197924 FKBPL_HUMAN (133-414): 4.04e-51: 178: 25.70		Q86SX1_HUMAN (1-262): 0: 505: 100.00
+	Hs
		111936 FKBP4_HUMAN (1-456): 1.79e-136: 402: 54.59		K9JA46_HUMAN (123-262): 1.08e-84: 269: 100.00
+	Hs
		431755 FKBP4_HUMAN (1-456): 1.79e-136: 402: 54.59		HS90A_HUMAN (123-262): 1.08e-84: 269: 100.00
+	Mm
		432409 FKBP4_MOUSE (1-444): 7.18e-136: 400: 55.38		HS90A_MOUSE (123-262): 7.34e-84: 266: 99.29
+	Hs
		438136 FKBP5_HUMAN (1-457): 6.63e-145: 423: 100.00		HS90B_HUMAN (141-262): 3.3e-74: 241: 94.26
+	Hs
		1020417 FKBP5_HUMAN (1-457): 6.63e-145: 423: 100.00		TRAP1_HUMAN (72-262): 1.93e-70: 231: 37.31
+	Hs
		438089 FKBP4_HUMAN (1-456): 1.79e-136: 402: 54.59		HS90B_HUMAN (141-262): 3.3e-74: 241: 94.26
+	Hs
		972530 FKBP4_HUMAN (1-456): 1.79e-136: 402: 54.59		Q6PK50_HUMAN (141-262): 5.12e-78: 241: 94.26
+	Hs
		972520 FKBP4_HUMAN (1-456): 1.79e-136: 402: 54.59		H90B4_HUMAN (152-262): 7.44e-56: 188: 82.88
+	Ce
		220015 O45418_CAEEL (18-445): 1.26e-112: 340: 38.52		HSP90_CAEEL (136-262): 9.16e-75: 242: 85.04
+	Hs
		111943 FKBPL_HUMAN (133-414): 4.04e-51: 178: 25.70		K9JA46_HUMAN (123-262): 1.08e-84: 269: 100.00
+	Hs
		431781 PPID_HUMAN (249-414): 4.11e-51: 178: 24.55		HS90A_HUMAN (123-262): 1.08e-84: 269: 100.00
+	Hs
		432312 AIPL1_HUMAN (125-419): 6.14e-51: 178: 19.89		HS90A_HUMAN (123-262): 1.08e-84: 269: 100.00
+	Hs
		432338 FKBPL_HUMAN (133-414): 4.04e-51: 178: 25.70		HS90A_HUMAN (123-262): 1.08e-84: 269: 100.00
+	At
		646588 FKB62_ARATH (31-247): 2.74e-52: 186: 40.99		HS901_ARATH (137-262): 1.62e-72: 236: 80.95
+	Hs
		438106 PPID_HUMAN (249-414): 4.11e-51: 178: 24.55		HS90B_HUMAN (141-262): 3.3e-74: 241: 94.26
+	Hs
		438598 FKBPL_HUMAN (133-414): 4.04e-51: 178: 25.70		HS90B_HUMAN (141-262): 3.3e-74: 241: 94.26