HitPredict

Interactor 1: FKBP5 (Q13451)
Peptidyl-prolyl cis-trans isomerase FKBP5 (PPIase FKBP5) (EC 5.2.1.8) (51 kDa FK506-binding protein) (51 kDa FKBP) (FKBP-51) (54 kDa progesterone receptor-associated immunophilin) (Androgen-regulated protein 6) (FF1 antigen) (FK506-binding protein 5) (FKBP-5) (FKBP54) (p54) (HSP90-binding immunophilin) (Rotamase)
Gene: FKBP5

Interactor 2: ANKY2 (Q8IV38)
Ankyrin repeat and MYND domain-containing protein 2
Gene: ANKMY2

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.47	0.50	0.489

Property	Details
Experiments	25036637
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	-
Homologous interactions	18

Homologous interactions

Color coding for hit scores

	1 457 Hs			1 441
+	Hs
		1034903 FKBP5_HUMAN (1-457): 6.63e-145: 423: 100.00		POTEE_HUMAN (4-432): 3.34e-45: 170: 13.81
+	Hs
		883504 FKBP5_HUMAN (1-457): 6.63e-145: 423: 100.00		RIPK4_HUMAN (3-276): 1.34e-39: 153: 14.18
+	Hs
		1034995 FKBP5_HUMAN (1-457): 6.63e-145: 423: 100.00		Q9H4D1_HUMAN (3-276): 4.21e-39: 151: 14.18
+	Hs
		883489 FKBP4_HUMAN (1-456): 1.79e-136: 402: 54.59		RIPK4_HUMAN (3-276): 1.34e-39: 153: 14.18
+	Hs
		972586 FKBP4_HUMAN (1-456): 1.79e-136: 402: 54.59		Q9H4D1_HUMAN (3-276): 4.21e-39: 151: 14.18
+	Mm
		673842 FKBP4_MOUSE (1-444): 7.18e-136: 400: 55.38		ANS1B_MOUSE (3-341): 4.79e-33: 134: 17.06
+	Hs
		1034933 FKBP5_HUMAN (1-457): 6.63e-145: 423: 100.00		ANKK1_HUMAN (139-378): 2.93e-14: 77.2: 8.84
+	Hs
		1053059 FKBP8_HUMAN (25-330): 3.36e-27: 114: 19.23		ANKY2_HUMAN (1-441): 8.31e-108: 327: 100.00
+	Hs
		556701 FKBP8_HUMAN (25-330): 3.36e-27: 114: 19.23		ANK1_HUMAN (1-373): 3.28e-58: 208: 12.12
+	Hs
		883512 FKBP8_HUMAN (25-330): 3.36e-27: 114: 19.23		RIPK4_HUMAN (3-276): 1.34e-39: 153: 14.18
+	Hs
		1053188 FKBP8_HUMAN (25-330): 3.36e-27: 114: 19.23		Q9H4D1_HUMAN (3-276): 4.21e-39: 151: 14.18
+	Hs
		259957 FKBP6_HUMAN (2-137): 2.27e-35: 135: 35.97		ZDH17_HUMAN (5-203): 8.27e-30: 124: 14.48
+	Hs
		684571 STIP1_HUMAN (265-457): 3.91e-23: 104: 17.62		RIPK4_HUMAN (3-276): 1.34e-39: 153: 14.18
+	Hs
		685027 STIP1_HUMAN (265-457): 3.91e-23: 104: 17.62		Q9H4D1_HUMAN (3-276): 4.21e-39: 151: 14.18
+	Hs
		883470 FKB1A_HUMAN (151-247): 2.87e-21: 90.3: 26.73		RIPK4_HUMAN (3-276): 1.34e-39: 153: 14.18
+	Hs
		923838 FKB1A_HUMAN (151-247): 2.87e-21: 90.3: 26.73		Q9H4D1_HUMAN (3-276): 4.21e-39: 151: 14.18
+	Hs
		684893 STIP1_HUMAN (265-457): 3.91e-23: 104: 17.62		ANKK1_HUMAN (139-378): 2.93e-14: 77.2: 8.84
+	Hs
		1053168 FKBP8_HUMAN (25-330): 3.36e-27: 114: 19.23		TANC1_HUMAN (26-100): 1.24e-09: 62.8: 36.00