HitPredict

Interactor 1: FKBP5 (Q13451)
Peptidyl-prolyl cis-trans isomerase FKBP5 (PPIase FKBP5) (EC 5.2.1.8) (51 kDa FK506-binding protein) (51 kDa FKBP) (FKBP-51) (54 kDa progesterone receptor-associated immunophilin) (Androgen-regulated protein 6) (FF1 antigen) (FK506-binding protein 5) (FKBP-5) (FKBP54) (p54) (HSP90-binding immunophilin) (Rotamase)
Gene: FKBP5

Interactor 2: NUDC3 (Q8IVD9)
NudC domain-containing protein 3
Gene: NUDCD3

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.71	0.60	0.656

Property	Details
Experiments	28363942, 35271311, 25036637
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005737 - cytoplasm GO:0006457 - protein folding
Homologous interactions	7

Homologous interactions

Color coding for hit scores

	1 457 Hs			1 361
+	Hs
		972546 FKBP4_HUMAN (1-456): 1.79e-136: 402: 54.59		NUDC3_HUMAN (1-361): 2.02e-159: 452: 100.00
+	Hs
		1035060 FKBP5_HUMAN (1-457): 6.63e-145: 423: 100.00		NUDC_HUMAN (7-343): 2.07e-102: 306: 27.38
+	Hs
		1053060 FKBP8_HUMAN (25-330): 3.36e-27: 114: 19.23		NUDC3_HUMAN (1-361): 2.02e-159: 452: 100.00
+	Hs
		1034946 FKBP5_HUMAN (1-457): 6.63e-145: 423: 100.00		NUDC2_HUMAN (191-344): 9.87e-31: 116: 19.11
+	Hs
		1053258 FKBP8_HUMAN (25-330): 3.36e-27: 114: 19.23		NUDC_HUMAN (7-343): 2.07e-102: 306: 27.38
+	Hs
		685120 STIP1_HUMAN (265-457): 3.91e-23: 104: 17.62		NUDC_HUMAN (7-343): 2.07e-102: 306: 27.38
+	Hs
		1284716 FKB10_HUMAN (134-285): 5.25e-13: 72.9: 20.51		NUDC1_HUMAN (155-282): 4.12e-26: 111: 20.93